Fluid/Electrolyte/Acid-Base Balance Flashcards
What are the 4 characteristics of body fluids?
Amount (volume)-Concentration (osmolality)-Composition (electrolyte Concentration)-Acidity (pH)
What percent of the body weight of an adult man is water?
60%
What percent of the body weight of an older man’s weight is water?
50%
What is the term for water that contains dissolved or suspended substances such as glucose, mineral salts, and proteins?
fluid
What are the two distinct compartments where body fluids are located? What proportion of the total body water is in each compartment?
-Extracellular Fluid (ECF) (1/3)-Intracellular Fluid (ICF) (2/3)
Where does fluid output occur? (5)
Kidneys-Lungs-Feces-Sweat-Skin
Where is most of the body water located?
ECF
What are the two major divisions of ECF?
Intravascular Fluid-Interstitial Fluid
What is the minor division of ECF?
Transcellular fluid
What is an electrolyte?
mineral salts in the body compartments
What is a cation?
positively charged ions
What is an anion?
negatively charged ions
Give 4 examples of cations in body fluids:
-Sodium (Na+)-Potassium (K+)-Calcium (Ca++)-Magnesium (Mg++)
What are 2 common anions in body fluids?
-Chloride (Cl-)-Bicarbonate (HCO3-)
What are the two different units for measuring electrolyte concentration?
-milliequivalents per liter (mEq/L)-millimoles per liter (mmol/L)
How is mEq/L calculated?
millimoles per liter multiplied by electrolyte charge
How is mmol/L calculated?
milligrams of electrolyte divided by its molecular weight that are contained in a liter of fluid being measured
Why is mEq/L used?
A milliequivalent of one electrolyte can combine with a milliequivalent of another electrolyte
What is osmolality?
a measure of the number of particles per kilogram of water
What determines the tonicity of a fluid?
The number of particles that cannot cross cell membranes easily
What is an isotonic solution?
A fluid with the same concentration of nonpermeant particles as normal blood
What is a hypotonic solution?
A fluid with a lower concentration of nonpermeant particles as normal blood (diluted)
What is a hypertonic solution?
A fluid with a greater concentration of nonpermeant particles as normal blood (concentrated)
What are the 4 basic ways in which water and electrolytes move between body compartments?
Active transport-Diffusion-Osmosis-Filtration
Which electrolytes are higher in the ECF than in the ICF?
Na+C-HCO3-
Which electrolytes are higher in the ICF than in the ICF?
K+Mg++PO4—
How do cells maintain their high intracellular electrolyte concentration?
active transport
What is the energy source for active transport?
ATP
What is required for diffusion of electrolytes across the cell membrane?
proteins (ion channels)
How does water move across the cell membrane?
Osmosis
What does a hypotonic IV do to the interstitial fluid?
dilutes it which causes water to move into the cells
What does a hypertonic IV do to the interstitial fluid?
concentrates it which causes water to leave cells
What is hydrostatic pressure?
the force of the fluid pressing outward against a surface
What is colloid osmotic pressure (oncotic pressure)?
an inward-pulling force caused by blood protiens that helps move fluid from the interstitial area back into capillaries
What are the three process that effect fluid homeostasis?
Fluid intake/absorption-Fluid distribution-Fluid output
Where is the thirst-control mechanism located in the brain?
hypothalamus
Who is at the highest risk of dehydration?
Infants-Patients w/ neurological/psychological disorders-older adults
How does fluid distribution between the extracellular and intracellular compartments occur?
osmosis
How does fluid distribution between the vascular and interstitial ports of the ECF occur?
filtration
Fluid output normally occurs through which 4 organs?
Skin-Lungs-GI tract-Kidneys
What are the 3 hormones that influence renal fluid excretion?
Antidiuretic hormone (ADH)-Adosterone-Atrial natriuretic peptide (ANP)
How does ADH regulate the osmolality of the body fluids?
influences how much water is excreted in the urine
How does the Renin-Angiotensin-Aldosterone System(RAAS) regulate ECF volume?
influences how much sodium and water are excreted in urine
How does atrial natriuretic peptide regulate ECV?
influences how much sodium and water are excreted in the urine
What are the 2 major types of fluid imbalanes?
Volume imbalances(extracelllar) and osmolality imbalances (concentration)
How does ECV deficit occur?
insufficient isotonic fluid in the extracellular compartment
Which condition is likely to occur during ECV deficit?
Hypovolemia
How does ECV excess occur?
too much isotonic fluid in the extracellular compartment
What are the 2 types of osmolality imbalances called?
hypernatremia and hyponatremia
What are the 2 general causes of hypernatremia?
loss of relatively more water than salt OR gain of relatively more salt than water