Fluid, Blood, HA Flashcards

1
Q

Where is erythropoietin produced?

A

Peritubular cells of the kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Petichiae indicate what diease?

A

Thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Lead poisoning anemia

A

Type, facts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the important risk factors for arterial thrombosis?

A

Smoking, HTN, high cholesterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What anemia causes bronze skin? How tx?

A

Siderobalstic anemia – “ringed” nuclei in bone marrow. B6 and bloodletting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which Thalassemias is often fatal in childhood mediterranean?

A

Beta-Thalassemias major. Small, pale RBs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is shock? 2

A

Inadequate tissue perfusion, compromised homeostasis (anaerobic metabolism)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Reed-Sternberg cell confirm what?

A

Hodgkin’s Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which Thalassemias is less severe and more common in Asia and africa?

A

Alpha-Thalassemias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Causes of Lymphadenopathy.. 4

A

Neoplastic disease, Immunologic or inflammatory conditions, Endocrine disorders, Lipid storage diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Posthemorrhagic anemia

A

Type, facts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the most common primary bone cancer?

A

Multiple Myeloma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Migraine 5 4 3 2 1

A

Unilateral, Pulsating, Moderate or severe pain, routine physical activity causes aggravation . 1 Nausea/vomiting and/or
Photo/phonophobia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What can cause coagulopathy?

A

Vitamin K deficiency, Liver disease, bad coagulation cascade, platelet abnormality, Meds (warfarin, etc)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lifespan of RBC is…

A

120 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What surgury exists for arterial thrombosis?

A

Angioplasty (w/wo stent), coronary artery bipass graft, endarterectomy (plaque removal)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What can cause Petechiae, Purpura, and Ecchymosis?

18
Q

Folate deficiency anemia

A

Type, facts

19
Q

Shock final common pathway is….

A

Metabolic acidosis/cell death

20
Q

What are the two types of hemopheila?

A

A: factor VIII deficiency (more common), Hemophilia B: factor IX Deficiency

21
Q

Hemolytic anemia

A

Type, facts

22
Q

Most common HA type…

A

Tension-type

23
Q

What are ocular associations (not causations) of migranes?

A

Hemianopsia, Horner’s syndrome, Normal Tension Glaucoma

24
Q

Amemia of chronic inflammation

A

Type, facts

25
What is the most common anemia world-wide? Affects ___%
Iron deficiency anemia. 20%
26
Define thrombocytopenia
Lower than the normal 150k -450k platelets per microliter of blood
27
Pernicious anemia
Type, facts
28
What is Virchow's triad?
Hypercoaguable state, vascular wall injury, and blood flow irregularity can lead to thrombosis (causing ischemia or infarction)
29
Aplastic anemia
Type, facts
30
"punched out" bone lesions indicate….
Multiple Myeloma
31
What causes "sea-fan" neovascularization?
Sickle cell retinopathy
32
What stage of RBC development does erythropoietin affect?
It affects the uncommitted pluripotent stem cell
33
Pernicous anema cause and effect.
Lack of vitamin b 12 from Intrinsic Factor deficiency, or genetic disorder. Effect is premature RBC death
34
95% of polycythemis has a mutation at ____
JAK 2 locus
35
What is Von Willebrand disesae?
Most common inherited bleeding disorder in less than 1% of people. Lack Von Willebrand factor, poor thrombus formation
36
What is the benign shooting pain in one eye and you don't know why?
Ophthalmodynia Periodica
37
Sideroblastic anemia
Type, facts
38
Iron deficiency anemia
Type, facts
39
What is anemic retinopathy?
Flame-shaped or dot-and-blot hemorrhages, Cotton-wool spots, Roth’s Spot (white hemorrhage)
40
Sjögren's Syndrome are 46 times more likely to develop….
Non-Hodgkin's Lymphoma
41
How long does it take to make RBCs?
4 days