Fluid and Electrolytes Flashcards
What is secreted at duodenum
bile
pancreatic enzymes
what is secreted at jejunum and ileum
bicarb
what is absorped at jejunum and ielium
Na+, Cl-, K+, water
what is secreted at colon
bicarb
K+
what is absorped at colon
Na+, Cl-, water
SGLT1 and B channels
transport Na_ in upper GI during the fed state
Na+ channel
transports Na+ and it located more ditally
Na+/H+ exchanger
Na+ moves down it’s conc gradient in exchange fro H+
Na+/K+ATPase
maintain conc gradent
K+ absorption
gets dragged along with water
K+ secretion
there is a net neg change in the lumen that attacks K+
Chloride-bicarv exchange
absorb cl-
secrete HCO3-
pull Cl- in as Na+ conc increases
chloride secretion
mediated by CFTR regulator
How do Ach, VIP, 5-Ht, prostaglands, histamines, cholera, and E. coli regulate CFR and the sodium - hydrogen ion exchanger (what is the mechanism)
2nd messenger generation
transport of Ach, VIP, 5-HT, prostaglands, histmaine, cholera, e coli,
stimulate CFTR
inhibit Na-H exchanger
result of Ach, VIP, 5-HT, PROSTAGLANDS, HISTAMINES, CHOLERA, E COLI
fluid secretion
location of Ach, VIP, 5-HT, prostaglands, histamines, cholera, e coli, somatostatin, enkephalin, ne
large and small insteine
mechanism is mineralocorticoid, glucocortiocid
transcriptional regulation
transport of mineralocoritcoid
glucocortioid
upertake of Na channels and Na/K ATPase
location of mineralocoritocid
colon
function of mineralocortioci, glucocorticoid, somatostatine, enkephalin, NE
fluid absorption
transport of somatostatine, enkephalin, NE
Na-K exchanger
osmotic diarrhea
caused by nonabosrobable nutrient
secretory diarrhea
caused by intestinal secretion of fluid and electrolytes
