Cell Physiology Flashcards

1
Q

Is myasthenia post or pre synaptic

A

post

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2
Q

what is going on in myasthenia gravis

A

antibodies form against nicotinic AcH receptors at NMJ causing muscle weakness

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3
Q

Is eaton-lambert post or pre synaptic

A

pre

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4
Q

what is going on in easton-lamber

A

antibodies form against voltage gated Ca++ channels, less Ca++ enters presynpatic terminal so less Ach released causing muscle weakness

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5
Q

is botulinum toxin pre or post synaptic

A

pre

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6
Q

what is going on with botulinum toxin

A

toxin cleaves SNARE proteins at NMJ causing muscle weakness

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7
Q

is alpha-bungarotoxin pre or post synaptic

A

post

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8
Q

what is going on with alpha bungarotoxin

A

peptide of bandedkriat venom irreversible blocks nicotinic AcH receptor

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