Cell Physiology Flashcards
1
Q
Is myasthenia post or pre synaptic
A
post
2
Q
what is going on in myasthenia gravis
A
antibodies form against nicotinic AcH receptors at NMJ causing muscle weakness
3
Q
Is eaton-lambert post or pre synaptic
A
pre
4
Q
what is going on in easton-lamber
A
antibodies form against voltage gated Ca++ channels, less Ca++ enters presynpatic terminal so less Ach released causing muscle weakness
5
Q
is botulinum toxin pre or post synaptic
A
pre
6
Q
what is going on with botulinum toxin
A
toxin cleaves SNARE proteins at NMJ causing muscle weakness
7
Q
is alpha-bungarotoxin pre or post synaptic
A
post
8
Q
what is going on with alpha bungarotoxin
A
peptide of bandedkriat venom irreversible blocks nicotinic AcH receptor