Flouride and Prevention Flashcards
Fluoride in nature
pale, yellow paste, widely distributed in nature and in our bodies
Sources of fluoride
Seafood (fish, clams, lobster, crab), tea, dry intact cereal,chicken products, artesian or deep wells, fresh surface water, seawater
Fluorine
chemical element
Where F is absorbed
80-95% in upper GIT and transported in plasma
**HE said he doesn’t like questions on numbers!!!
% absorbed in first 30 min
40%-95%
**HE said he doesn’t like questions on numbers!!!
F ingested on an empty stomach F produces a peak _____ level within ____ min/hours?
plasma in 30 min
F binds with ____ and other ______ and _____ _____
Calcium, divalent and trivalent cations
5mg F is cleared in ______
8-9 hours
F is deposited in ____
calcified tissues such as bone, teeth
F poisoning
accidental or intentional ingestion of F containing products
Elevated levels of F –>
chronic F toxicity
F handling is regulated by _____ and in the marketplace by the _____
Occupational Safety Health Legislation and FDA
Probable toxic dose (PTD)
defined as the minimum does that could cause toxic signs and symptoms, including death
Emergency Rx for F toxicity (immediate and non)
milk or milk and egg
vomitting
oral calcium of aluminum
maintenance of blood calcium with intravenous calcium
Emergency F overdose (less than 5mg)
give calcium orally (milk) and observe for a few hours
induced vomitting is not necessary
more than 5mg F overdose
ER room-pump stomach- not with downs or mental retardation tho
give oral calcium
F more than 15mg overdose
hospital immediately-induce vomitting
Cardiac monitoring; observe peak T waves and watch for shock
F therapies
F gel, foam, and varnish
F supplements
Salt F
Milk F
Post eruptive mechanism of action of F
promotes remineralization of enamel, inhibits demin of early carious lesion, inhibits glycolysis in which sugar is converted to acid by cariogenic bacteria
Pre eruptive mechanism of action of F
improves enamel crystallinity, reduces enamel solubility in acid, improves tooth morphology
Topical F
applied directly to and absorbed by the surface of the teeth
-can be home gel, dentrifice, mouth rinse, professional, or water
Systemic F
taken into the body by consuming products containing F
-water, dietary, dentrifice,dietary supplement
% of toothpastes which are F
79-90% in US
**HE said he doesn’t like questions on numbers!!!
how F in toothpaste is taken up
by dental plaque directly and demineralized tissue