Fisiología de la Coagulación Flashcards

1
Q

Vida media de una plaqueta

A

8-10 días

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2
Q

Deficiencia de factor VIII

A

Hemofilia A

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3
Q

Endotelio Basal

A

Antitrombotico

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4
Q

Entodelio Actico

A

Protrombotico

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5
Q

Trombosis Arterial

A

Lesion Arterial
Alta presion
Decadas
Ateroesclerotico

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6
Q

Trombosis Venosa

A

Estasis
Baja presion
Ocurre rapido
»> fibrina

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7
Q

Receptores en Plaquetas ricos en leucinas

A

GP Ib/IX/V
Segundo mas abundante

R FVW

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8
Q

Receptores en Plaquetas Inmunoglobulinas

A

GP VI

Señalización y activación plaquetaria

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9
Q

Receptores en Plaquetas 7 dominios trasnmenbrana

A

Receptores de trombina
ADP, PAR 1, PAR 4, TXA2

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10
Q

Funcion GP IIb/IIIA

A

Esencial para la union a fibrionogeno

Mas abundante

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11
Q

Pasos de la hemostasia primaria

A

Vasoespasmo
Adhesion
Activación
Agregación

TAPON

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12
Q

Via Larga Coagulacion

A

12–>11–>9–8–>10

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13
Q

Via Corta Coagulacion

A

FT–> 7–>FT7a–>10

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14
Q

TTPa que mide

A

Via intrinseca

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15
Q

TP/INR que mide

A

Via extrinseca y comun

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16
Q

Vía comun

A

10–5–Protrombina–Fibrinogeno

17
Q

Reestablecer flujo y cicatrizar

A

Fibrinolisis

18
Q

Cascada enzimática de la fibrinolisis

A

Plasminogeno–> plasmina–> lisis de fibrina

19
Q

Activadores fiblinolisis

20
Q

Dimeros D elevados

A

Nos hablan de fiblinolisis

MUY INCREMENTADOS__> CID