First Aid: Breast Pathology Flashcards
Name that tumor: Small, mobile, firm mass with sharp edges in the stroma and most common in patients under 35. When does it enlarge and increase in tenderness? is it a precursor to breast cancer? is it benign or malignant?
Fibroadenoma. increases in size and tenderness with estrogen (pregnancy and prior to menstruation). NOT a precursor to cancer. Benign.
Name that tumor: small tumor that grows in lactiferous ducts and typically is beneath the areola. it results in a serous or bloody nipple. is there an increased risk of cancer?
intraductal papilloma. yes (1.5-2x) increase in risk for carcinoma.
Name that tumor: large bulky mass of CT and cysts and most common in the 5th decade. what type of projections are associated with this?
Phyllodes tumor. ‘leaf-like’ projections. (older women like to garden- plants/leaves)
___________: during breastfeeding, increase risk of bacterial infection through cracks in the nipple. what would you treat it with?
Lactational mastitis. Dicloxacillin and continued breastfeeding.
what is benign, usually painless lump and forms as a result of breast tissue injury?
Fat necrosis.
what usually shows up on mammography with a fat necrosis?
calcification
what does Paget disease result from?
underlying DCIS or invasive breast cancer.
how does Paget disease present on the breast?
eczematous patches on nipple.
what type of malignant breast cancer is the most common?
invasive ductal
_____ presents as firm, fibrous, rock-hard mass with sharp margins and small, glandular and duct-like cells?
invasive ductal
_______: is a malginant breast tumor which shows orderly row of cells (‘indian file’) due to decreased E-cadherin expression
Invasive lobular
what type of invasive malignant breast tumor shows Peau d’orange (breast skin resembles orange peel) and neoplastic cells block lymphatic drainage? it’s often mistaken for mastitis or paget disease.
inflammatory. often mistaken for mastitis or paget disease.
