Final practice questions Flashcards

1
Q

When does gastrulation occur in gestation?

A

3rd week of gestation

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2
Q

What event signals the onset of gastrulation?

A

formation of the primitive streak

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3
Q

What is the primary goal of gastrulation?

A

establish the 3 primary germ layers

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4
Q

Which surface of the embryonic disc does the primitive streak appear?

A

dorsal

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5
Q

Which end of the embryonic disc does the primitive streak first appear?

A

caudal

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6
Q

Which structure establishes the major axis of the embryo?

A

primitive streak

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7
Q

Which end is the primitive node located?

A

cephalic

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8
Q

What causes the elongation of the primitive streak?

A

epiblast cells migrating through the streak into the median plane

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9
Q

What is invagination during gastrulation?

A

migration of epiblast cells through the primitive streak into the median plane

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10
Q

What does the hypoblast layer become?

A

the endoderm layer

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11
Q

What happens in the epiblast cells that invaginate after the hypoblast layer has been displaced?

A

they differentiate into mesoderm

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12
Q

What germ layer does the epiblast layer become after the mesoderm layer has formed?

A

ectoderm

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13
Q

What is the result of invagination?

A

3 primary germ layers are formed

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14
Q

What germ layers are produced during gastrulation?

A

ectoderm, mesoderm, endoderm

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15
Q

Which germ layer gives rise to the epithelial lining of the digestive tract?

A

endoderm

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16
Q

Which embryonic tissue gives rise to the ectoderm, mesoderm, and endoderm?

A

epiblast

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17
Q

Which event initiates the development of the notochord?

A

aggregation of mesoderm cells immediately beneath the primitive streak

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18
Q

Around which embryonic structure do vertebral bodies eventually form?

A

notochord

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19
Q

What is the remnant of the notochord in the developed vertebral column?

A

nucleus pulposus

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20
Q

When in utero does neurulation occur?

A

around the 3rd week

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21
Q

What is the ultimate goal of neurulation?

A

formation of the brain and spinal cord

22
Q

Which primary germ layer gives rise to the brain and spinal cord during neurulation?

23
Q

What triggers neurulation?

A

chemical signals from the notochord

24
Q

What cells develop at the lateral margins of the neural plate?

A

neural crest cells

25
As the neural groove deepens, it forms _____________
neural folds
26
When do somites disappear?
during neurulation as the neural tube is forming
27
What type of embryonic tissue forms neural crest cells?
ectoderm and neuroectoderm (ectoderm is general answer, neuroectoderm is specific answer)
28
What structure gives rise to neural crest cells?
neural plate
29
What nervous system structures do neural crest cells form?
PNS, ganglia, glia cells, meninges
30
How does the neural tube form?
neural folds fuse with each other in the midline
31
When do the neural folds begin to close to form the neural tube?
in week 4
32
Which region on the trilaminar disc does the neural tube initially close?
cervical
33
When is neurulation complete?
when the caudate pore closes
34
What does the cranial/rostral end of the neural tube become?
brain
35
What does the portion distal to the cranial/rostral end of the neural tube become?
spinal cord
36
When does development of the vertebral column occur in the embryo?
during the 4th week of development
37
Which portion of the embryonic vertebrae does the sclerotome become that surrounds the notochord?
centrum (which becomes the vertebral body after ossification)
38
Which portion of the embryonic vertebrae does the sclerotome become that surrounds the neural tube?
neural arch (which becomes the vertebral arch after ossification)
39
Which embryonic structure forms the nucleus pulposus?
remnant of notochord
40
What type of embryonic tissue gives rise to neuroblast cells?
neuroepithelial cells
41
What type of cell give rise to gray mater?
neuroblast cells
42
When do the clusters of gray matter appear in the primordial spinal cord?
around the 6th week of development
43
What are the names of the 2 clusters of gray matter in embryonic spinal cord?
alar plate and basal plate
44
What type of cells give rise to the alar and basal plates of the primordial spinal cord?
neuroblast cells
45
Interneuron cell bodies are found in the _________ cluster of gray matter and motor neuron cell bodies are found in the _________ cluster of gray matter of the developing spinal cord
alar, basal
46
Which vertebral structures begin to fuse during the first year of life?
neural arches
47
What is the name of the nerve that innervates the vertebral column?
recurrent meningeal n.
48
What types of fibers are found in recurrent meningeal nerves?
both sensory and motor fibers
49
What are the names of the 2 branches that come off the dorsal rami?
medial branch and lateral branch
50
What are the names of the 3 connective tissue membranes that protect the spinal cord and nerve roots?
dura mater, arachnoid mater, and pia mater
51
What is the name of the structure that wraps around nerve roots as they exit the IVF?
dural root sheath
52
What space is found between the vertebral periosteum and the dura mater?
epidural space