Final PP 2018 Flashcards
which wre the AA with 4 carbons?
Asp
Thr
Asn
(remember AThA)
which AA have 2 chiral centers?
Iso
Thr
what is the definition of turnover number?
maximum number of substrate converted to product per second by each active site
which AA are non-polar?
Go And Trake Vital Part In Promoting Mother Language Gly Ala Try Val Pro Iso Phe Met Leu
what kind of disease is the Gilberts syndrome?
un-conjugated bilirubin
anticoagulant produced by the endothelial cells?
NO tPA prostacyclin ADPase heparan-sulfate
which state has higher affinity to O2?
R
what is the job of 23BPG in the RBC?
to stabilize the T state
promotes the release of remaining O2
how does phosphorylation effects pyruvate kinase?
inhibits it
what are the allosteric activators/inhibitors of pyruvate kinase?
activators- fructose-1,6-BP
inhibitors- ATP, Alanine
what is the reaction catalyzed by Methionine AdenosylTransferase?
ATP+Met->SAM+PPi+Pi
what is the enzyme synthetizing GABA?
what is the cofactor?
write down the reaction
glutamate decarboxilase
PLP
Glu+H->GABA+CO2
which enzyme def. will lead to orotic aciduria?
UMP synthase
converts orotic acid to UMP
how many 23BPG molecules bind Hg?
1
what are the cofactors for pyruvate DH?
lipoic acid FAD NAD CoA TPP
