Final part 3 Flashcards
when substrate binds to an enzyme, the enzyme changes shape this reaction is called:
induced fit
Which carries vesicles by “walking” along microtubules of the cytoskeleton?
motor protein
What are proteins that are tagged with ubiquitin and taken into its core and degraded?
proteasome
In the following reaction, which molecule is the reducing agent? Glyceraldehyde triphosphate + NAD+ → diphosphoglycerate + NADH + H+
glyceraldehyde triphosphate
Fatty acids can enter the metabolic pathway at which point?
Formation of Acetyl coA
The oxygen consumed during cellular respiration is involved directly in which process or event?
Accepting electrons at the end of the electron transport chain
An enzyme catalyzes a reaction by:
lowering the activation energy of a reaction
At high concentrations, ATP binds to the allosteric site of phosphofructokinase, which catalyzes the third step in glycolysis. Binding of ATP causes a conformational change that halts enzyme activity and prevents overproduction of ATP. Which of the following best describes the type of enzymatic reaction taking place?
feedback inhibition
In the following reaction, which molecule is reduced?
6 CO2 + 6 H2O + light energy -> C6H12O6 + 6 O2
CO2
The first enzyme in glycolysis which catalyzes the phosphorylation of glucose, binds glucose and ATP:
Hexokinase
In the formation of purines (components of nucleic acids), tetrahydrofolate is very important. Tetrahydrofolate is formed from the reaction of dihydrofolate with dihydrofolate reductase (DHFR). To treat leukemia, scientists developed a drug called methotrexate that prevents cancer cells from forming purines. Methotrexate binds to DHFR and prevents formation of nucleic acids by cancer cells but does not alter conformation of DHFR.
WHAT IS THE SUBSTRATE IN THIS REACTION AND WHAT IS THE BEST CATEGORY FOR THE REACTION INVOLVING METHOREXATE?
- dihydrofolate
- competitive inhibition reaction
In the energy-yielding or payoff phase of glycolysis, energy is extracted in the form of:
NADH and ATP
Which is the major source of electrons for the electron transport chain?
NADH
In the citric acid cycle, what is the molecule that binds to acetyl CoA?
Oxaloacetate
Which kind of metabolic poison would most directly interfere with glycolysis?
one that closely mimics the structure of glucose but is not metabolized