FINAL: Lower GI Tract Flashcards

1
Q

What is the difference between exocrine and endocrine

A

exocrine glands secrete substances into a ductal system to an epithelial surface, endocrine glands secrete products directly into the bloodstream

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2
Q

What is the exocrine function of the pancreas

A

Pancreatic enzymes (acinar cells)
- involved in the GI tract, attached directly to the pancreatic duct

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3
Q

What is the endocrine function of the panreas

A

Hormones (islets of Langerhans)
- do not attach to pancreatic duct, release insulin/glucagon directly into the capillaries

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4
Q

What are the pancreatic hormones that function to balance glucose levels in our body

A

Insulin and glucagon

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5
Q

How does insulin balance glucose levels in the body

A
  • it is released in response to high blood glucose levels
  • stimulates cells to take up glucose for use
  • stimulates liver to store additional glucose as glycogen
    Fed stage - think glucose is IN
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6
Q

What is glycogen

A

The storage form of sugar in between meals

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7
Q

How does glucagon function to balance glucose levels in our body

A
  • it is released in response to low blood glucose
  • stimulates release of stored glucose
    Think glucose is GONE
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8
Q

What is diabetes

A

A disease defined by high levels of blood glucose

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9
Q

What is type 1 diabetes

A

Total lack of insulin production
- usually an autoimmune attack on the pancreas

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10
Q

What is type 2 diabetes

A

Insulin resistance ( problem with cell signaling and cell receptors)
- pancreas still releases insulin

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11
Q

What is the function of the large intestine

A

Reabsorption of water and salts, resulting in feces
About 1.5 meters long

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12
Q

What are the four regions of the large intestine

A

Ascending (includes cecum and appendix)
Transverse
Descending
Sigmoid

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13
Q

What are the structures that help with muscle contractions to move feces

A

Tenia coli: longitudinal bands (muscularis)
Haustra: sacs/pockets
Epiploic appendages: lobules of fat

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14
Q

What is the appendix

A

Vermiform (worm-shaped) tube, role in immune system of the gut

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15
Q

what is the cecum

A

The wider section of the ascending colon

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16
Q

What happens in the large intestine?

A
  • digestive tract receives about 9 liters of water a day - only about .2 liters are lost in feces
  • process relies on osmosis
  • more solute (ions and proteins) in tissue and blood rather than in lumen
  • water diffuses from lumen into tissues and blood
  • many diseases disrupt this function
17
Q

What are gut microbiome and their function

A
  • the microorganisms found in our gut
  • they change throughout life
  • can be impacted by genetics and the environment
  • major function is secretion of metabolically important molecules
18
Q

What is the function of the rectum

A

Holds feces until defecation

19
Q

What is the function of the anal canal and how does it work

A

Feces gets passed through the anal canal during defecation
Anal canal is controlled by two sphincters
- internal -> involuntary
- external -> voluntary
Mucosa layer is stratified and produces extra mucus during defecation