final labx Flashcards
Iron deficiency anemia
hypo chromic MCH low microcytic MCV low anisocytosis poikilocytosis MCHC low ferritin low <10 transferrin saturation low <5-10% TIBC increased MOST COMMON BABY ANEMIA starts at 6 mo milk anemia
blood loss anemia
cause: trauma/surgery
increased neutrophils SHIFT TO LEFT
normocytic/chromic MCH normal
Chronic Blood loss anemia
cause: menstruation, fibroids, cancer, angiodysplasia
angiodysplasia
blood vessel malformation in the GI increased platelets hypochromic MCH low poikilocytosis reticulocytosis
poikilocytosis
asterisk shaped RBCs
reticulocytosis
immature RBC’s looks like there are granules in the cells
megaloblastic anemia
macrocytic
magaloblast=immature RBC
B12, or B9 or deficiency, or both
Megaloblastic anemia W/B12 deficiency
potentially irreversible nervous system pathology known as
subacute combined degeneration of spinal cord aka lichtheim disease= posterior and lateral column demyelination (madness)
pernicious anemia
autoimmune
can’t make enough RBCs due to inability to absorb B12
autoantibodies against parietal cells, intrinsic factor, receptors for intrinsic factor for the ilium
aplastic anemia
bone marrow and blood stem cells are damaged
inability to generate mature RBCs=
-anemia, leukopenia, thrombocytopenia
pancytopenia
pancytopenia
deficiency of all three cellular components of the blood (red cells, white cells, and platelets).
sideroblastic anemia
ringed sideroblasts produced instead of healthy RBCs
hereditary (x linked)
acquired due to: myeloma, leukemia, RA, SLE, cirrhosis, drugs and toxins, B6 copper deficiency
heart disease
liver damage
kidney failure
hemolytic anemia
thalassemia, sickle cell G6pd jaundice gallstone formation pulmonary hypertension
the infectious microorganism associated with hemolytic uremic syndrome in children
e coli
