Final Final Final Stuff Flashcards

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1
Q

spermatogenisis

A

forms 4 haploid sperm cells

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2
Q

oogenisis

A

haploid egg and polar bodies

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3
Q

fertilization step

A

egg is not accessible

sperm releases acrosome to dissolve top layer

sperm actin binds to egg and penetrates inside to cytoplasm

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4
Q

development is characterized by ______

A

coordinated change

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5
Q

coordinated changes during development

A

change in size
change in biochemistry and physiology
change in form and functionality

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6
Q

developmental periods

A

cleavage (fertilization)
Patterning (germ layers)
Differentiation (special tissue)
Fetal Growth (get big)

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7
Q

describe the cleavage phase

A

zygote to blastocyst

trophoblast forms outside and inner cell mass the inside

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8
Q

what are the two layers of the trophoblast?

A

cytytrophoblast (inner)
Synciotrophoblast (outer)

together they form the placenta

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9
Q

gastrulation phase

A

formation of germ layers from primitive streakq

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10
Q

ectoderm

A

skin, cns, pigment

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11
Q

mesoderm

A

heart, muslce, kidney, rbc, smooth muscle, digestive

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12
Q

endoderm

A

lungs, thyroid, pancreas

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13
Q

neurulation

A

notochord forms in mesoderm, tells ectoderm to form neural tube (CNS)

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14
Q

organogenisis

A

follows gastrulation and folding, limbs take shape

most systems have developed by week 8

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15
Q

fetal period (9-38 weeks)

A

growth. Premature birht before 38 weeks, can live 30 weeks without help and 22 can survive with it

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16
Q

neural crest cells

A

surround the neural tube and become

neurons, ganglia, cartilage, bone, connective tissue, adrenal cells, neurons, glia, pigment cells

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17
Q

DDT

A

male reproductive disorders

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18
Q

male disorders

A

low sperm counts, testicular cancer, undescended testes, male breast cancer

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19
Q

hypospadius

A

urethra out the bottom

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20
Q

epispadius

A

urethra out the top

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21
Q

where can you find ribosomes?

A

rough ER, nucleus, free floating

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22
Q

cystic fibrosis

A

CFTR sequence has deleted Phe leading to mutation of chloride channel which causes chlorine to stay in the cell and mucous builds on the outside. Protection against cholera

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23
Q

kinetic energy types

A

thermal, electromagnetic, electrical

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24
Q

potential enrgy types

A

chemical, mechanical, nuclear, gravitational

25
Q

how and where does glycerol enter glycolysis?

A

as DHAP, forms 1 NADH before entering. Requires 1 ATP

26
Q

b oxidation occurs in the

A

mitochondrial matrix

27
Q

fascilitated diffusion

A

carrier mediated passive transport

28
Q

primary active transport

A

uses ATP to pump against gradient

29
Q

secondary active transport

A

couples the movement of an ion down its concentration gradient with the movement of another molecule against its concentration gradient

30
Q

characteristics of carrier mediated transport

A

specificity, saturation, competition

31
Q

glucose transporters 1-4

A

1: basal uptake and high affinity
2: low affinity, glucose sensing
3. Basal uputake and high affinity
4. Dynamic at the membrane

32
Q

Paracrine/ Autocrine signaling

A

communication with neighboring cells through increased concentration gradient of messenger

33
Q

juxtacrine signaling

A

non-secretion, cell to cell signaling

34
Q

VX gas

A

inhibits acetylcholinesterase

35
Q

cholera toxin

A

stim formation of cAMP which opens CL channels in intestine, activates nA pump. Leads to crazy diahrea.

36
Q

resting membrane potential, K, NA

A

-70, -96, +62

37
Q

lidocaine

A

blocks sodium voltage gated channels so action potentials can’t be generated

38
Q

absolute refractory period

A

dudring depolarization, can’t generate another action potential

39
Q

relative refractory period

A

repolarization and hyperoplarization, AP can be generated but only with a larger than normal stimulus

40
Q

contiguous conductino

A

unmylenated action potential propogation

41
Q

saltatory conduction

A

mylenated, channels concentrated at nodes

42
Q

Multiple Sclerosis

A

autoimmune attack of myelin, degeneration of axons. Tingling, numbness, balance and coordination probems

43
Q

threshold

A

-55 mv, NA close and K open at 30

44
Q

EPSP

A

excitatory post synaptic potentail (NA in, K out)

45
Q

IPSP

A

inhibitory post synaptic potential (K out)

46
Q

Temporal summation

A

adding epsps and ipsps from same presynaptic neuron at high frequency

47
Q

spatial summation

A

adding epsps and ipsps from 2 presynaptic neurons onto 1 post synaptic neuron

48
Q

precinaptic facilitaiton/inhibition

A

one presynapic neuron acts on another to release more or less neurotransmitter onto post synaptic neuron

49
Q

GPSP

A

combo of all e/ipsps on post synaptic neuron at the same time. WIll it fire?

50
Q

interneurons found in

A

CNS

51
Q

Astrocytes

A

most abundant glial cell, maintain structure and order of brain

surround cleft and gontaine glutamate transporters to remove it after exocytosis
provide neurons with nutrients, regulate bloodflow, form BBbarrier

52
Q

high synaptic GLU

A

damage to cytoskeleton, membrane, and dna. Happens with brain injury, hearing loss, alzheimer,s parkinsons, huntingtons

53
Q

oligodendrocytes

A

make myelin in CNS, up to 50 neurons

54
Q

schwann cells

A

make myelin in PNS, up to 1 neuron

55
Q

microglia

A

immune cells of CNS, phagocytosis

56
Q

ependymal cells

A

form epithelium, secrete CSF, contain cilia for CSF movement, stem cell qualities

57
Q

post concussion

A

low frontal lobe function

58
Q

meninges (inside out)

A

PAD