Final Exam Review Packet 1 Flashcards
Serotonin is a monoamine or catecholamine
a monoamine
Dry mouth might be a side effect of
a noradrenergic agonist (e.g., a tricyclic antidepressant)
Which of the following might be likely to increase appetite?
a. a 5HT2C agonist
b. methylphenidate
c. a D2 antagonist (e.g., an antipsychotic drug)
c. a D2 antagonist (e.g., an antipsychotic drug)
What effect do carbohydrates have on serotonin in the brain?
Increase 5HT because facilitate transport of tryptophan into brain.
Explain why MAO inhibitors are anti-depressants
They reduce breakdown of monoamines.
Explain why monoamine reuptake inhibitors are anti-depressants.
They prolong action of monoamines.
If serotonin synthesis is blocked, which of the following might be increased?
Depression
Aggressive behavior
What is 5-HIAA?
Metabolite of 5HT
In a study that followed 49 preadolescent males for four years, why were monkeys with the lowest levels of 5-HIAA much more likely to die?
Aggressive behavior led to injuries
What is the name of the dopamine path that disintegrates in Parkinson’s disease?
nigrostriatal
Sexual motivation (libido) would be most likely to be suppressed by:
Serotonin
In addition to behavior therapy, what type of pharmacotherapy would be most likely to help someone with OCD?
Serotonin agonist
What type of electrical stimulation would be likely to increase dopamine release, and where?
Electrical stimulation of the substantia nigra
Would increase release of DA in basal ganglia
How might dopamine deficiency relate to vulnerability to addiction?
(specify a part of the brain, and explain)
Deficiency in nucleus accumbens
How might a dopamine deficiency relate to ADHD?
(specify a part of the brain)
Deficiency in prefrontal cortex – maybe also nucleus accumbens