Final Exam - Don't Knows Flashcards
what is paraformaldehyde fixative used for
fluorescent studies and research
what is glutaraldehyde fixative used for
EM and kidneys
what is the permissible exposure limit for formaldehyde in the workplace (short term)
2 ppm over a 15 minute period
what is hanks special solution used for
cytogenetics and genetic mutations
what does chloroform do to tissue
clears fatty tissue and increases alcohol penetration
what is zenker’s fixative used for
nuclear chromatin, connective tissue fibers, and cytoplasmic features
what does alcohol do to tissue
coagulates proteins and causes shrinkage
what is RPMI special solution used for
flow cytometry and lymphoma
when was the first recorded autopsy performed and on who
44 B.C. on Julius Caesar
explain the Rokitansky autopsy method
organs are removed in situ (where it originated) in one block from neck to rectum
what is the average weight of a 20-30 year old prostate
15 g
what is the average weight of a 16-20 year old spleen
170 g
what is the average weight of a left lung
375 g
what is the average weight of combined female kidneys
288 g
what is average weight of a right lung
475 g
what are the four types of pericardial effusion
transudative, exudative, hemorrhagic, and malignant
when should a PAD be finished according to the joint commission for hospital accreditation
2 days
where are stress ulcers most commonly located
stomach
what is caput succedaneum
accumulation of interstitial fluid in the soft tissues of the scalp - head becomes edematous and swells
what is the most common, important pathologic finding associated with birth head injuries
intracranial hemorrhage
what is craniorachischisis
neural tube defect that causes both anencephaly and bony defect of the spine
coarctation of aorta is associated with which syndrome
turner syndrome
what are the most common teratomas of childhood
sacrococcygeal teratomas
what does the ADAM complex stand for
amniotic deformities, adhesions, mutilations
what are two common fetal findings in fetal alcohol syndrome cases
deceased brain weight
agenesis of the corpus callousum
what is the single largest cause of neonatal deaths globally
infections - they usually arise from the placenta
what is the CPT code for a foreskin from someone other than a newborn
88304
what is ENE
extra nodal extension - metastasis of tumor to lymph node (through the lymph node’s capsule)
what is the CPT code for a hemorrhoid
88304
what is the CPT code for aortic valves
88305
what is the most common type of malignant salivary gland tumor
mucoepidermoid carcinoma
krukenberg tumors are most common in which four locations
stomach, colon, appendix, and breast
what is the CPT code for a frozen section
88331
which three conditions can cause lipomas
gardner syndrome
adiposis dolorosa
familial multiple lipomatosis
what’s an important thing to look for with salivary gland specimens
nerves
what is the CPT code for a spermatocele
88304
what is the CPT code for lymph nodes and lung specimens
88305
what is the CPT code for skin tags
88304
define an adverse event
any error that would have resulted in a sentinel event but was caught and did not affect the outcome in a negative way - a “near miss”
what is the most common salivary gland tumor in infants/chidlren
hemangioma
what are sialoliths mainly made of
carbonate apatite
what is the most common type of nasal papilloma
inverted
which salivary gland is the most common gland for tumor
parotid
what is the CPT code for a POC less than 20 weeks
88305
what is the CPT code for vulvar tags
88305
what is the CPT code for a tonsil specimen from a younger patient
88300
what is the CPT code for a hernia
88302
what is the most common type of parotid tumor
pleomorphic adenoma
define polkilodermatous
variegated appearance
where do malignant laryngeal lesions most commonly arise
vocal cord
what is the CPT code for lymph nodes
88307
what is the CPT code for a parathyroid gland
88305
what should you submit for a papillary thyroid lesion
1 section/cm
where is squamous cell carcinoma most commonly located in the mouth
floor of mouth
lateral/ventral surfaces of tongue
a tumor of which size differentiates a T1 and T2 lip and oral cavity tumor
<2 cm = T1
>2 cm = T2 and beyond
what is a papilloma
benign, HPV associated papillary wart often caused by types 6 and 11
what is the leading cause of death worldwide
TB
what is the most common type of lung cancer
adenocarcinoma - a type of non-small cell lung cancer
what is small cell carcinoma
includes neuroendocrine tumors and carcinoids
usually adjacent to bronchi
what is large cell carcinoma
a type of non-small cell lung cancer that is diagnosis by exclusion
HIV infection is associated with an increase risk of _______
TB
what are the two main subtypes of lung adenocarcinoma
mucinous vs non-mucinous
what can asbestos cause
mesothelioma
what are the 5 basic histologic patterns of non-mucinous lung adenocarcinoma
acinar
papillary
micropapillary
lepidic
solid
which stage involves the pleura
T2 and above
what is the difference between a high anterior resection and a low anterior resection
high: cut above the anterior serosal reflection (no mesorectal tissue)
low: cut below the anterior serosal reflection (mesorectal tissue shows)
define hematochezia
passage of fresh blood through the anus
which device is used to give proximal and distal donuts of colon resections
anvil
which staging system is used for anal/rectal malignancies
TNM
what is another name for the circumferential radial margin
mesorectal margin
NET make up ____ % of small bowel t
50%
signet-ring cell carcinoma causes what
linitus plastica (leather bottle appearance)
50% of Meckel’s diverticulum have what on cut section
ectopic gastric mucosa or pancreatic parenchyma
what is the gross appearance of a yolk sac tumor
yellow tan with focal myxoid/gelatinous areas with focal hemorrhage
what is the CPT code for a ureter
88307
what is another name for a myelolipoma
incidentaloma
what are the four main morphologic patterns of bladder tumors
papilloma
invasive papillary carcinoma
flat non-invasive carcinoma (CIS)
flat invasive carcinoma
tumor invasion into the periureteric fat stages a ureter to what
pT3
what are the 5 variants of renal cell carcinoma
clear cell
papillary
chromophobe
Xp11 translocation
collecting duct
what is the critical size for an adrenal tumor
<5 cm - pT1
>5 cm - pT2
what is a simple prostatectomy
large chunks of the prostate are removed in the case of benign prostatic hyperplasia
weigh, measure in aggregate, and do not ink because there is no capsule
what is the gross appearance of a seminoma
homogeneous, gray white lobulate surface
what are the two benign, neoplastic conditions of the kidney
angiomyolipoma
oncocytoma
sprionolactone bodies are seen in which condition
adrenal cortical adenoma
a male radical cystectomy can be oriented anterior/posterior using what primary structure
peritoneal reflection - it is much shinier on the posterior aspect
what is a myelolipoma (incidentaloma)
adrenal tumor with mature adipose tissue and normal bone marrow elements
what is the difference in gross appearance of a small and large adrenal pheochromocytoma
small: yellow-tan
large: hemorrhage, necrosis, and cystic
which kidney lesion is variegated and poorly demarcated with necrosis, hemorrhage, and cystic change
adrenal cortical carcinoma
what are corpora amylacea
amyloid bodies found in the damaged prostate - note and removed before submitting section
what is waterhouse-friderichson syndrome
bacterial infection of the adrenals causes major adrenal insufficiency which leads to hypertension
what is the most common testicular tumor in infants/children up to 3 years of age
yolk sac tumor
what is Conn syndrome
excessive cortisol production by the adrenal cortex
a kidney tumor that invades the renal vein is staged as what
pT3a - regardless of tumor size
what is the CPT code for a hydrosalpinx/hemosalpinx
88305
what is SEE-FIM and what is its importance
sectioning and extensively examination the fimbriated end
a specific way of grossing a fallopian tube for a prophylactic removal due to BRCA gene
what can a blunted fallopian tube indicate
PID
what is the important size for omentum staging
2 cm
what is important about grossing adenosarcomas of the endometrium
staged based on tumor size (5 cm) and infiltration
what is Rokitansky’s protuberance
nipple-like structure covered with hair in an ovarian teratoma
important to submit as it has the highest possibility to undergo malignant change
what is considered stage 1 cervical cancer
confined to cervix
what is an important measurement for an endometrial cavity
cornu to cornu
what is an endometrioma
chocolate cyst caused by endometriosis
what is the CPT code for fallopian tubes for ectopic pregnancy
88305
what is important about grossing endometrial carcinoma/sarcomas
need to submit full thickness sections
note how deep (< or > 50%) the invasion is into the myometrium
what is considered stage 0 cervical cancer
carcinoma in situ
what is the CPT code for uterine prolapse
88305
which two stains can be useful for confirming cervical intraepithelial lesions
Ki-67 and p16
what is a common appearance of adenomyosis
trabeculation
where are you most likely to find serosal endometriosis
corneal regions and posterior cul-delsac
define AGUS
atypical glandular cells of underdetermined significance
define ASCUS
atypical cells of undetermined significance
what is the CPT code for the uterus for something other than prolapse or malignancy
88307
what is a nabothian cyst
cyst on the cervix or in the endocervical canal - note and submit one section
what is the normal length range for an umbilical cord
50-70 cm long
what is the CPT code for a placenta in the first or second trimeste
88305
what is the normal amount of cord coiling
2 coils per 10 cm
what is the normal diameter of an umbilical cord
0.8-1.3 cm
what is a circumvallate insertion
membranes insert before the disc margin/edge and have fibrin deposition that forms a palpable ridge
what is important to note about the staging of invasive breast carcinoma
based on tumor size and involvement of skin/chest wall
what is the appearance of medullary breast carcinoma
soft fleshy mass
what is the CPT code for a breast reduction
88305
what is the CPT code for a sentinel lymph node
88307
what is the appearance of ductal carcinoma
firm grey-pink stellate mass
what is PASH
pseudoangiomatous stroma hyperplasia
shows anastomosing slit-like spaces
which breast lesion has a radial scar and grossly resembles carcinoma
complex radial sclerosing lesion
what is an important feature of a serous cystadenoma of the pancreas
central stellate scar
congenital cysts of the pancreas are associated with which two conditions
PKD and von-hippel
what is the CPT code for traumatic finger/toe amputations
88302
what is the CPT code for exostosis (osteochondroma)
88305
what is the CPT code for non-traumatic extremity amputations
88307
what is an important pertinent negative in amputation cases
depth and involvement of underlying bone
what is the CPT code for a gout smear
89060
what is the CPT code for a femoral head not for fracture
88304
what is the most important staging factor for bone
tumor site
what are two important measurements to take for an above the knee amputation
proximal soft tissue margin to heel and heel to toe
which condition accounts for 82% of amputations in the United States
poor vascular health
what is the CPT code for bone fragments/pathological fracture
88307
what is the CPT code for bone resection
88309