Final Bio Exam Flashcards
Amphipathic
Molecules with both polar and nonpolar regions
Emergent Properties of Water
1. Cohesion - polar & nonpolar interactions between molecules
2. Moderation of Temperature - high specific heat capacity
3. Insulation by Floating Ice - solid H₂O less dense compared to liquid H₂O
4. Solvent of Life - very common solvent
Suspension
Large particles in mixture that settle out
What is a sphere of H₂O atoms around an ion called?
Hydration Shell
Emulsion
Mixture of 2 or more liquids that don’t usually mix
pH
-log[H⁺]
Isomers
Chemical compounds w/ the same formula but different structures
Saturated
Hydrocarbon with only single C-C bonds (has as many Hs as possible; no double C=C bonds)
Unsaturated
Hydrocarbon with at least one double C=C bond (does not have the maximum number of H atoms)
Poly-unsaturated
Hydrocarbon with multiple double C=C bonds (at least 2)
What are molecules with a hydroxyl group called?
Alcohols
What is a molecule with a carbonyl group on the outside called?
- Aldehyde
- Molecule names end with “-al”
What is a molecule with a carbonyl group on the inside/middle (between two Cs) called?
- Ketone
- Molecule names end with “-one”
What is a molecule with a carboxyl group called?
- Organic Acid
- Weak Acid
What is a molecule with an amino group called?
Amine
What is a molecule with an amino group and a carboxyl group called?
Amino Acid
What is a molecule with a sulfhydryl group called?
- Thiols
- Ends with “-thiol”
What is a molecule with a phosphate group called?
Organic Phosphate
What are the four macromolecules?
- Carbohydrates
- Lipids
- Proteins
- Nucleic Acids
Sugars are denoted by:
“-ose” in the name of a molecule
Sucrose =
Glucose + Fructose
Lactose =
Galactose + Glucose
Maltose =
Glucose + Glucose
Polymers of Glucose
- Starch
- Glycogen
- Cellulose
Properties of Starch
- Moderately branched
- Used for storage in plants
Properties of Glycogen
- Highly branched
- Storage polymer for animals
Properties of Cellulose
- Unbranched
- Found in the cell wall of plants
- Structural polymer
What are the bonds in polysaccharides?
Glycosidic Linkage
What are the bonds in lipids?
Ester Linkage
What are the bonds between amino acids / in proteins?
Peptide Bonds
What are the bonds in nucleic acids?
Phosphodiester Linkage
What are the properties of saturated fats?
- Usually solid
- Arranged straight
What are the properties of unsaturated fats?
- Usually liquid
- Arranged w/ kinks
- Not good for you usually
Cis fats?
Hydrogens are on the same side, making a bent shape
Trans fats?
Hydrogens are on opposite sides, making a straight shape
Hydrogenation
The process of adding hydrogen atoms to a molecule to break the double bond (process to conver unsaturated molecules to saturated ones)
Phospholipid
- Hydrophilic head
- Hydrophobic tail(s)
- Used in phospholipid bilayers
Steroid Structure
4 Carbon rings (6C, 6C, 6C, 5C)
Fat Structure
- 1 glycerol
- 3 fatty acids
Quaternary Structure
Proteins with 3 or more chains/subunits
Tertiary Structure
3-D model of proteins
Secondary Structures
Structures that make up a protein (like alpha-helixes and beta-sheets)
Primary Structure
The amino acid sequence of a protein
What stabilizes tertiary structure? (Interactions)
- Hydrogen bonds between side chains
- Van der Waals (hydrophobic interactions)
- Ionic Bonds
- Disulfide Bridges
Prion
- Misfolded Protein
- Can induce misfolding in normal variants of the same protein, causing cell deaths
Monomers of proteins?
Amino Acids
Monomers of Carbohydrates?
Monosaccharides
Monomers of Nucleic Acids?
Nucleotides
What is a nucleotide made of?
- Phosphate Group
- Sugar
- Nitrogenous Base
Pyrimidine
Nitrogenous base w/ just 1 ring (6C)
Which bases are pyrimidines?
- Cytosine (C)
- Uracil (U)
- Thymine (T)
Purine
Nitrogenous base w/ 2 rings (6C, 5C)
Which bases are purines?
- Adenine (A)
- Guanine (G)
What sugar is used in RNA?
Ribose
What sugar is used in DNA?
Deoxiribose
How many base pairs in 1 human DNA?
3 billion base pairs
3 Domains of Life
- Archaea
- Bacteria
- Eukarya
Glycocalyx
Slime layer or capsule in bacteria and prokaryotes
Nucleus
- Where DNA is stored
- Nuclear Pores (holes in membrane)
- Nuclear Membrane (double membrane) made of phospholipids and proteins
- Contains Nucleolus, which produces rRNA (ribosomal RNA) and ribosomes
- Controls cell activity
Rough Endoplasmic Reticulum
- Contains Ribosomes
- Secretes proteins
- Site of protein synthesis
Smooth Endoplasmic Reticulum
- Produces Lipids
- Metabolizes Carbohydrates & Steroids
- Detoxification
- Produces Vesicles
Ribosome
- Large & Small Subunit
- Produce Proteins
- Made of rRNA and proteins
Vesicle
- Phospholipid bilayer + proteins
- Transports materials
Golgi Apparatus
- Modifies lipids & proteins
- Sends them to destinations in vesicles
Mitochondrion
- Produces ATP
- Site of cellular respiration
- Has its own ribosomes & DNA (maternal)
Lysosome
- Hydrolytic enzyme (involved in hydrolysis)
- “Clean up” organelle
- Prevents viruses and invaders
Central Vacuole
- Only found in plant (and fungal) cells
- Storage organelle
- Stores water and macromolecules
Chloroplast
- Consists of Thylakoids (light reactions) and stroma (Calvin cycle)
- Has its own ribosomes and DNA
Microtubule
- Part of Cytoskeleton for cell shape
- Polymer of Tubulin
Cytoskeleton
Gives cell its shape
Centriole
- Produces spindle fibers
- Primary microtubule-organizing center
Fluid Mosaic
Mosaic of lipids (phospholipids), proteins, carbohydrates to form a membrane
Glycoprotein & Glycolipid
- Protein/Lipid attached to oligosaccharide
- Modified Protein/Lipid
- Involved in cell-to-cell recognition, virus-to-cell recognition, and bacteria-to-cell recognition (entity-to-cell recognition)
What is one role of cholesterol?
To control fluidity of membrane (makes viscous ones more fluid and fluid ones more viscous)
Membrane Protein Roles
- Intercellular joining
- Enzyme activity
- Transport
- Cell-to-cell recognition
- Signal Transduction
Active Transport
- Uses energy from ATP to transport
- Against the gradient
Passive Transport
- Small molecules diffuse easily
- Facilitated & Simple Diffusion
- With the gradient
Facilitated Diffusion
- Ions
- Large and polar (even if uncharged)
Simple Diffusion
- Hydrophobic molecules
- Small, uncharged polar molecules
Phosphorylation
Inorganic Phosphate (from ATP hydrolysis) binds to molecule, causes a conformational change
Conformational Change
Change in the shape (and therefore the function) of a protein due to phosphorilation
Dephosphorylation
- Loss of a phosphate group (inorganic phosphate detaches from molecule)
ATP Hydrolysis
ATP → ADP + Pᵢ
ATPase activity
Bulk Transport
- For large molecules
- Requires ATP
Pinocytosis
Cell eats droplets of extracellular fluid with molecules in it (nonspecific)
Phagocytosis
Eats a cell or bacteria
Macrophage
“big eater” cell eating
Pseudopod
Extension of cytoplasm around entity
Receptor Mediated Endocytosis
- Receptors on the cell grab the molecule and then endocytosis occurs
Metabolism
Totality of organism’s chemical reactions
Catabolic
Reactions that break down
Anabolic
Reactions that synthesize/build
Distal Phosphate Group
Very last/one furthest away from the ATP
Exergonic
Spontaneous
Endergonic
Non-spontaneous
Coupling
Spontaneous process helps trigger non-spontaneous process