Final Flashcards
Lose control of limbs, then trunk
Immune response after a viral infection
Reversible demyelinated
Guillain-Barre
Neuron at rest
Sodium and chlorine high outside the axolemma
Potassium and proteins high inside the axolemma
Resting potential of neuron
-70mV
How do we maintain unequal charge?
Channels
Sensory movement
Afferent divisions of PNS
10 million
Collect info, about internal body environment
Visceral sensory neurons
Collect info, about external environment and body position
Somatic sensory movement
Exterceptors
Monitor touch, pressure, temp. Sight, smell, hearing
Monitor joints and muscles
Proprioceptors
Monitor digestion, urinary, reproductive, pain, taste
Interceptors
Receptors deliver..
Info to the CNS for processin
Efferent division of PNS
Send directions from CNS to muscle and glands
Motor neurons
Smooth m., cardiac glands, fat
Visceral motor neurons
Skeletal m.
Somatic motor neurons
Most located in CNS-pyramidal and parkinje
20 billion in body
Interneurons
The middle men
A) distributes sensory info
B) coordinate motor signals- the more complex the action, more Interneurons we involved
Association cells
Most numerous in CNS
Directs growth of neurons
Composed of BBB
astrocytes
Make and circulate CSF
Ependymal cells
Oligodendrocytes
Myelinate the CNS making internodes
Gaps in myelin called “modes of Ranvier”
Police force of CNS
Garbage chewers
Microglia
Monitor environment of cell
Like astrocytes in CNS by function
Satellite cells
Myelinated axons in PNS
Act like Oligos in CNS
Important in Wallerjam degeneration
Schwann cell
Passive, always open, maintains resting potential
Leak channels
Active, restores resting potential, ejects 3 NA+ for every 2 K+ brought in
NA/K ATPASE pump
Active, open in response to stimulus. Changes the resting potential= depolarizers, repolarizes the cell
Gated channel
Occurs in most membranes
Weak- diminishes w/ distance
Depolarize, no threshold reached
Usually does not turn into action potential unless received lad to axon hillock
Graded
Occurs in exciteable in cells Strong stimulus Excited the entire length of the cell Depolarize to threshold Action potential form
Action potential
Single synapse, repeated stimuli
Temporal summation
Spatial summation
Multiple synapses, stimulatianous stimuli
If threshold is reached, action potential will be generated and passed along axon
All or none principle
Differences in the speed of AP
Propagation
Unmyelinated axons, ap runs in small steps as signals continue to be repeated
Continuous
Myelinated axons, a.p. Signal conducts only at the nodes of Ranvier, leaping over the internodes
Saltatory
Largest diameter, myelinated ap travels over 300 mph
Type A fibers
Medium diameter, myelinated ap travels at 40 mph
Type B fibers
Smallest diameters, Unmyelinated, ap travels at 2 mph
Type C fibers
So we have an ap now what?
Release of neurotransmitter from synaptic bulb
NTs have ethier excitatory or inhibitory effects in body.
1st discovered, excitatory at NMJ
Acetylcholine
Inhibitory in motor cortex
Prevents overstimulation of muscles
Induces hyper polarization
If receptors are destroyed then causes ridged/ stiff muscles
Dopamine
Receptors are destroyed then causes rigid / stuff muscles
Parkinson’s disease
Excitatory in Limbic system
Causes depolarization and ap to occur
Dopamine
Blocks the re-uptake of dopamine- you get high
Cocaine