FINAL 02 - Adrenergic Drugs

Question 1

Neurotransmitter released by SNS and binds to smooth and cardiac muscles

Answer 1

Noradrenaline (Norepinephrine)

Question 2

Hormone released by the adrenal medulla that circulates in the blood supply

Answer 2

Adrenaline

Question 3

Hormone released during a fight or flight response

Answer 3

Adrenaline

Question 4

Contracts smooth muscle (Type of receptor)

Answer 4

α Receptor

Question 5

Relaxes smooth muscles in the gut (Type of receptor)

Answer 5

α Receptor

Question 6

Relaxes smooth muscle (Type of receptor)

Answer 6

β Receptor

Question 7

Contraction of cardiac muscle (Type of receptor)

Answer 7

β1 receptor

Question 8

2 catecholamines used as endogenous agonists (AN)

Answer 8

Adrenaline, Noradrenaline

Question 9

DOC for anaphylactic shock (General adrenergic agonists)

Answer 9

Adrenaline

Question 10

Used as a vasodilator, vasopressor, and stimulant (General adrenergic agonists)

Answer 10

Ephedrine

Question 11

Used as a nasal decongestant (General adrenergic agonists)

Answer 11

Pseudoephedrine

Question 12

A β1 agonist used for cardiogenic shock (Adrenergic agonists)

Answer 12

Dobutamine

Question 13

An α2 agonist used for hypertensive crisis (BP of 160/100); its brand name is Catapress (Adrenergic agonists)

Answer 13

Clonidine

Question 14

__________ and __________ is used as a nasal decongestant and for bloodshot eyes (Adrenergic agonists) (OX)

Answer 14

Oxymetazoline, Xylometazoline

Question 15

__________ and __________ is used as a bronchodilator (General adrenergic agonists) (II)

Answer 15

Isoprenaline (Isoproterenol), Isoetharine

Question 16

__________, such as soterenol, salbutamol (albuterol), and salmeterol, are used for asthma (Adrenergic agonists)

Answer 16

β2 agonists

Question 17

__________ and __________ are general α1 and β blockers (Adrenergic antagonists) (CL)

Answer 17

Carvedilol, Labetalol

Question 18

Examples of ___________ include prazosin, doxazosin, and terazosin (Adrenergic antagonists)

Answer 18

α-Blockers

Question 19

Blockers used for benign prostatic hyperplasia; causes orthostatic hypotension (Adrenergic antagonists)

Answer 19

α-Blockers

Question 20

An α-blocker also used as an antidepressant (Adrenergic antagonists)

Answer 20

Mirtazepine

Question 21

__________ β-blockers are nonselective (Generations of β-blockers)

Answer 21

1st generation

Question 22

__________ β-blockers are selective β blockers (Generations of β-blockers)

Answer 22

2nd generation

Question 23

__________ β-blockers are β1 blockers (Generations of β-blockers)

Answer 23

3rd generation

Question 24

Dichloroisoprenaline, pronethalol, and propranolol are examples of __________ β-blockers (Generations of β-blockers)

Answer 24

1st generation

Question 25

1st generation β-blocker with partial agonist activity (Adrenergic antagonists)

Answer 25

Dichloroisoprenaline

Question 26

1st generation β-blocker whose off-label use is for anxiety (Adrenergic antagonists)

Answer 26

Propranolol

Question 27

It is contraindicated with asthma (Generations of β-blockers)

Answer 27

1st generation β-blockers

Question 28

Practolol, acebutolol, metoprolol, and betaxolol are examples of __________ β-blockers (Generations of β-blockers)

Answer 28

2nd generation

Question 29

Innovator of atenolol

Answer 29

Tenormin

Question 30

Epanolol, primidolol, and xamoterol are examples of ___________ β-blockers (Generations of β-blockers)

Answer 30

3rd generation

Question 31

β-blockers that start with A-M are usually __________

Answer 31

Selective

Question 32

β-blockers that start with N-Z are usually __________

Answer 32

Nonselective

Question 33

___________ and ___________ are drugs that affect the biosynthesis of adrenergics (Drugs affecting adrenergic transmission) (αα)

Answer 33

α-Methyltyrosine, α-Methyldopa

Question 34

__________ is a drug that inhibit the uptake of NA into storage vesicles (Drugs affecting adrenergic transmission)

Answer 34

Reserpine

Question 35

__________ and ___________ are drugs that inhibit the release of NA from storage vesicles (Drugs affecting adrenergic transmission) (GB)

Answer 35

Guanethidine, Bretylium

Question 36

Desipramine, imipramine, amitriptyline, reboxetine, duloxetine, venlafaxine, bupropion, methylphenidate, atomoxetine, cocaine, tyramine, amphetamine, and ephedrine are drugs that inhibit the reuptake of NA into __________ (Drugs affecting adrenergic transmission)

Answer 36

Presynaptic neurons

Question 37

__________ such as phenelzine, iproniazid, tranylcypromine, and meclobemide are drugs that inhibit the metabolic enzymes (Drugs affecting adrenergic transmission) (PITM)

Answer 37

Monoamine oxidase inhibitors (MAOIs)

Question 38

__________ is a drug that act as antagonists of the α2-adrenoceptors (Drugs affecting adrenergic transmission)

Answer 38

Mirtazepine