FEMALE REPRODUCTIVE SYSTEM 2 Flashcards
ORDER of follicle maturation
- Primordial follicle
- Unilaminar primary follicle
- Multilaminar primary follicle
- Antral or vesicular follicle
- Mature, preovulatory or graafian follicle
The oocyte is surrounded by the follicular cells which are
separated by the ____ _________ from the stromal
cells.
basement membrane
Follicles that are formed during fetal life.
Primordial Follicles
IN Primordial Follicles, Oocytes are enveloped by a single layer of ______
epithelial (follicular) cells.
flattened
Primordial Follicles → Found within the ovarian _______.
cortex
Most of the primordial follicles are found near the _________ __________
tunica
albuginea
After activation by FSH primordial follicles become the
_______ follicles
primary
primary follicles Two types:
Unilaminar and Multilaminar.
epithelium lining of the unilaminar primary follicle
SINGLE layer of simple cuboidal epithelium
also appears on this stage
− functions to activate sperm cells during the
fertilization
Zona pellucida
Continuous proliferation of the follicular cells will form from a unilaminar primary follicle
Multilaminar primary follicle
Multilaminar primary follicle lining epithelium
stratified follicular epithelium follicular cells
stratified follicular epithelium follicular cells are now called
granulosa cells
in Multilaminar primary follicle Stromal cells outside the follicle differentiate into ______
layers.
Theca
is a group of endocrine tissues that are highly
vascularized
Theca interna
Theca interna produce ___________hormone
androstenedione
Theca externa is composed of _________ and _______
muscles
fibroblast; smooth
fibroblast in the multilaminar follicle will produce ______ _____ to support the structure of the whole follicle
collagen fibers
smooth muscles will respond to ___ during the ___
surge. They respond by contracting. If these smooth here in
theca externa will contract, they will put pressure on the follicle,
causing it to rupture and release the ovum through a process
called _________.
LH; LH; ovulation
Theca interna in a microscopic slide has the presence of clear areas in their cytoplasm, it is because of?
ADROSTENEDIONE
Explanation: steroid hormone derived from cholesterol, meaning they have storing lipids as the theca interna cells convert cholesterol into steroid hormones.
__________ cells are also capable of producing steroid
hormones. Thus, there are clear areas in their cytoplasm
representing lipids.
Granulosa
the special relationship between the cells of the theca
interna and the granulosa cells.
androstenedione to estradiol (androgen to estrogen)
theca interna will reply to LH by converting ___________ into ____________ which will diffue through the basement membrane into the granulosa cell
cholesterol; androstendione
granulosa cell will respond to FSH by activating its enzyme
___________ and it will convert androstenedione into
_______
aromatase; estrogen
Secondary or Antral Follicles As the follicle grow, they move deeper into the ______
cortex
Secondary or Antral Follicles Within such follicles, spaces appear between the granulosa
cells as the cells secrete follicular fluid called________.
antrum
Mature or Preovulatory or Graafian Follicles Forms_______at the ovary surface.
bulge
graafian follicle is forming a bulge of the surface of the ovary
because it is just waiting for the surge of _for it to burst and
release the egg cells
LH
Additional structures we only see on a mature follicle:
Corona Radiata, Cumulus oophorus
granulosa cells that directly surround the oocyte;
accompanies the oocyte after ovulation.
Corona Radiata
forms the hillock that provides support to the egg cell.
Cumulus oophorus
what links the corona radiata or egg cell to the rest of the
granulosa cells is the _______ ________
cumulus oophorus
