CARTILAGE Flashcards

1
Q

Tissue =

A

Cells and Extracellular matriX

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2
Q

ECM OF CARTILAGE IS RICH IN

A

chondroitin sulfate

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3
Q

fibers of cartilage, what collage

A

type II collagen

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4
Q

one of the glycosaminoglycan that allow cartilage to withstand compression

A

chondroitin sulfate

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5
Q

Synthesize the fibers and ground substance

A

CHONDROCYTES

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6
Q

Bone, tendon, skin, dentin

A

type 1 collagen

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7
Q

type 1 collagen funciton

A

resistance to tension

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8
Q

collagen type 2 tissues

A

cartilage, vitreous body

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9
Q

type 2 collage is _______ not easily seen under the miscroscope

A

highly refractile

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10
Q

function of collagen type 2

A

resistance to pressure

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11
Q

collagen type 3 tissue

A

reticular fibers

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12
Q

collagen type 3 function

A

supports parenchyma of organs

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13
Q

collagen type 4 tissues

A

basement membrane

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14
Q

collagen type 4 funciton

A

sheet-forming collagen

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15
Q

collagen type 7 tissue

A

basementmembrane

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16
Q

collagen typ e7 function

A

anchors basal lamina to reticular lamina

17
Q

The matrix immediately surrounding the lacunae
is more intensely BASOPHILIC

A

TERRITORIAL MATRIX

18
Q

This is due to the masking of the collagen fibers
by the high concentration of the
____________ in the ground substance. (basophilia)

A

glycosaminoglycans

19
Q

retains water thus allowing
cartilage to act as shock absorber.

A

Ground substance

20
Q

why prone to OA?

A

chondrocyte no longer produce ECM

21
Q

FUNCTIONS OF THE CARTILAGE

A

Shock absorber
Provide framework and support
Protects underlying tissue
Provides flexibility
Provides template for bone formation

22
Q

Dense irregular connective
tissue covering of
cartilages

A

perichondrium

23
Q

perichondrium 2 layers

A

fibrous
chondrogenic

24
Q

Chondroblasts in perichondrium differentiate into chondrocytes, start producing matrix, and add to existing cartilage beneath the perichondrium.

A

Appositional Growth:

25
Q

proliferation and hypertrophy of existing chondrocytes.
It occurs within the cartilage.
Chondrocytes will divide (mitosis) producing isogenous aggregates that deposites ECM making chondrocytes move away from each other.

A

Interstitial growth

26
Q

Hyaline:
Nuclei:
formation:

A

Elliptical shape at periphery
isogenous cell groups

27
Q

Similar to hyaline cartilage except that is
contains abundant network of elastic fibers

A

ELASTIC CARTILAGE

28
Q

elastic cartilage is elastic fibers +

A

collagen II

29
Q

Elastic cartilage is found in

A

Ear (auricle)
Epiglottis
Eustachian tube

30
Q

skinfold of the ear is made up of what epithelium

A

stratified squamous keratinized epithelium

31
Q

ntermediate between dense connective tissue
and hyaline cartilage

A

FIBROCARTILAGE

32
Q

Rich in collagen 1

A

FIBROCARTILAGE

33
Q

toughest among all collagen

A

collagen 1

34
Q

Fibroblast: Chondrocytes occur singly or ____ isogenous
aggregates

A

aligned

35
Q

_____immediately surrounding the
chondrocytes has type 2 collagen

A

Matrix

36
Q

Isogenous aggregates of chondrocytes are separated by _____ collagen fibers

A

type 1

37
Q

Chondrocytes are ________ and with ___ metabolic rate

A

immobile; low

38
Q

extensive damage causes the perichondrium to produce a scar of _____ connective tissue

A

dense

39
Q

outer fibrous layer will cause the _________ to deposit collagen fibers in the collagen tissue forming a scar

A

fibroblast