Fatty Acid Biosynthesis Flashcards
0
Q
To move Acetyl CoA out of mitochondria, convert it to
A
Citrate
1
Q
Fatty acids store carbon AND electrons. Electrons are stored as
A
reduced carbon - CH2 which will later oxidize to CO2
2
Q
What can cross the mitochondrial membrane?
A
pyruvate
citrate
malate
3
Q
what cannot cross the mitochondrial membrane?
A
NADPH
NADH
Acetyl CoA
4
Q
what is the rate limiting step?
A
Acetyl CoA carboxylase
carboxylation of Acetyl CoA
5
Q
What is the product of the rate limiting step?
A
Malonyl CoA - acetyl CoA with CO2
6
Q
what are the five stages of Fatty acid synthesis?
A
Loading of the precursors via thioester derviatives condensation of precursors reduction dehydration reduction
7
Q
How do you make ODD numbered Fatty acids?
A
odd numbered FA chains are built with proprionyl group (c3) instead of acetate (c2)
