Fat Flashcards
Why should fats be added to the diet?
- decrease dust
- lubricate fee processing
- binder
- glossy hair coat
- increase diet energy density
- provide EFAs
Lipid classification (R)
- simple lipids - esters of FAs and various alcohols (TG)
- compound lipids - phospholipid
- derived lipids - derived from hydrolysis of simple and compound lipids that still possess the general properties of lipids
- Sterols - lipids with complex ring structure (cholesterol)
FA nomenclature depends on? (R)
- chain length
- degree of saturation (# DB)
- orientation of DB (usually cis)
Which FAs are essential?
linoleic and alpha linolenic acids
- cell membrane formation
- precursors of eicosanoids –> PGs, leukotrienes, thromboxanes (oxygenation)
What is the structure of a triglyceride?
one molecule of glycerol + 3 FAs
What are sterols?
- most common cholesterol
- essential component of cell membranes
- serves as precursor for:
1. vitamin D
2. chalice acid
3. steroid hormones
Functions of phospholipids?
- formation of cell membranes
- important constituent of lipoproteins
- thromboplastin
- nervous system insulators
- donors of phosphate radials
What are glycolipids?
- CHO + lipid
- important for structure in nerves, white matter in brain
- function by sending signals to accelerate cell transport and cell knowledge of different presented components (part of gate keeping system)
How do lipids get to horse?
- ingested in feed
- released from storage (long term negative energy balance or between meal energy release)
- synthesized by liver (triglycerides)
When would there be a need for significant release of lipids between meals?
when glucose funds out
What is the problem regarding the structure of fat?
fats are insoluble, but enzymes of digestion require an aqueous environment
- therefore, must be emulsified by biliary salts
Explain fat digestion
- occurs minimally in mouth (lingual lipase)
- mostly in small intestine (bile salts and lipase) –> mixed micelle (MAG, DAG, FFA, cholesterol, phospholipids) so they can be absorbed by enterocyte
- absorbed into intestinal epithelial cells (FA –> TAG) + binding proteins = lipoprotein complexes) AND cholesterol –> transportation (as chylomicrons)
- delivered via lymphatics and capillaries to tissues
- transported throughout body as chylomicrons
- digested fat provide over 2.25x more utilizable energy than equal weight of digested carb/protein
More energy means?
- increased growth rates, milk production, reproduction efficiency, physical performance
Explain the process of fat metabolism in the liver
Using lipoprotein lipase
- hydrolyze TG –> FFAs and glycerol
Fatty acids –> adipose + skeletal muscle (used as fuel or storage)
TG –> liver (glucose synthesis)
Fat as an energy source
- FA oxidation (in liver) –> acetyl CoA (citric acid cycle)
- ketogenesis - acetyl CoA –> acetoacetate + hydroxybutyrate (ketone bodies) = important metabolic fuel for cells outside of liver
Essentiality of dietary fat for horses
- to absorb fat soluble vitamins (A,D,E,K)
- to provide source of linoleic and (n-6) linolenic acid (n-3)