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Meccanismi molecolari > Farmaci > Flashcards

Farmaci Flashcards

1
Q

Farmaci contro EGFR nel carcinoma polmonare

A

gefitinib: qualsiasi linea
erlotinib: 1° mutati, 2° e 3° non futati
afatinib: 1° mutati

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2
Q

Farmaci contro EGFR nel carcinoma al colon retto

A

cetuximab e panitumumbab
impediscono il binding con egf

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3
Q

Farmaci contro KRAS

A

FTI inh: blocco la prenilazione
G12C inh (sotorasib): blocco scambio GDP-GTP

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4
Q

Farmaci contro MEK

A

trametinib
bimetinib
cobimetinib

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5
Q

Farmaci contro RAF

A

vemurafenib: blocco atp
dabrafenib
encorafenib

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6
Q

Farmaci contro CDK4/6

A

palbociclib
ribociclib
abemaciclib

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7
Q

BH3 mimetici

A

venetoclax
navitoclax
amg176

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8
Q

Farmaci contro PARP

A

olaparib
rucaparib
nicaparib

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Meccanismi molecolari (7 decks)

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