FA 2016 279-284 Flashcards
Where is ANP released from?
Atrial Myocytes
What is the function of Atrial Naturetic Peptide
constrict the efferent arterioles and dilate affrerent arterioles promoting dieresis in response to increase BP
What contributes to Aldosterone Escape Mechanism?
ANP
what is released from ventricular myocyte in response to increase tension?
BNP
what is used for diagnosing HF?
BNP (Very good negative predictive value)
what is the recombinant form of BNP for treating HF?
Nesiritide.
aortic arch receptors is transmitted via what nerve?
vagus
carotid sinus receptors is transmitted via what nerve?
Glossophrangeal nerve
What take the stimulus from CN9 & CN10 to the medulla?
Sensory Afferent Fibers
what part of the medulla do the sensory afferent fibers take the stimulus to?
solitary nucleus of Tractus
what is the triad of the cushing reaction?
Hypertension, bradycardia and respiratory depression
In a chemoreceptor, what 3 things stimulates aortic arch and carotid sinus?
Inc 02, dec C02 AND dec pH (acidic)
what part of the body does not directly respond to p02?
Brain
Pulmonary Capillary pressure is a good estimator of
LAP
Measured with a right heart Catheter?
PCWP
PCWP>LVDP in what disease?
mitral stenosis
what factors is responsible for Autoregulation in the heart?
Adenosine, NO, Co2 and dec 02
What amino acid makes NO?
arginine
what factor is responsible for auto regulation in the brain?
C02
What factor is responsible for auto regulation in skeletal muscles
CHALK ( c02, H+, Adenosine, Lactate, K+)
auto regulation in the skin
Sympathetic stimulation (most important) temp control
what are the causes of EDEMA?
inc capillary pressure (e.g HF)
dec Plasma protein (e.g Nephrotic syndrome, liver failure & protein malnutrition)
inc capillary permeability (e.g toxins, infection & burns)
increase interstitial fluid colloid pressure (inc lymphatic blockage)