F212 Nucleic Acids Flashcards
Functions of DNA
Replication
Protein Synthesis
DNA
Deoxyribose Nucleic Acid
Polynucleotide
Usually double stranded
Nucleotide
The monomer of nucleic acids consisting of a phosphate, a sugar and an organic base
RNA
Ribonuclease Acid
Polynucleotide
Usually single stranded
Bases
DNA
A
T
C
G
Bases
RNA
A
U
C
G
Bases
A
Adenine
Bases
C
Cytosine
Bonds Between Bases
A-T
Two hydrogen bonds
Bonds Between Bases
C-G
Three hydrogen bonds
Bases
T
Thymine
Bases
G
Guanine
Pyrimadines
Single ring
C
T
U
Purines
Double ring
A
G
Bases
U
Uracil
Complimentary Base Pairs
DNA
C-G
A-T
DNA - Replication
Stages
Double helix is untwisted
Hydrogen bonds between the strands are broken exposing the bases
Free DNA nucleotides are hydrogen bonded to the exposed bases on both strands
Sugar phosphate bonds are formed along the back bone of the new DNA strands
Recoil to form double helices
Two new exact replica DNA molecules have been formed
DNA polymerase
Enzyme that forms sugar phosphate bonds along the backbone of a strand of DNA
Complimentary Base Pairs
RNA
U-A
C-G
Bonding Between Bases
Hydrogen bonding
There are two bonds between A and T
There are three bonds between C and G
Distance Between Bases
Each complimentary base is made up of a pyrimidine and a purine so the chains of DNA are always the same distance apart
DNA
Anti Parallel
The two strands in DNA run parallel to each other but in the opposite direction, anti parallel
DNA
Double Helix
The anti parallel chains twist, like twisting a rope ladder to form the final double helix structure
DNA - Replication
Process
Semi-conservative replication
Gene
Definition
A sequence of DNA nucleotides that codes for a polypeptide
Role of DNA
Protein Synthesis
-The sequences of bases on DNA code for the sequence of amino acids in proteins
Roles of RNA
Protein Synthesis
- RNA nucleotides form a complimentary strand, mRNA
- mRNA leaves the nucleus through a nuclear pore and attaches to a ribosome
- tRNA molecules bring amino acids to the ribosome in the correct order according to the sequence of bases on the mRNA