Extras Flashcards
Nl minute ventilation
7L/min (14 rr x 500 ml)
FEV1, FVC, and the ratio in restrictive vs obstructive disease
Restrictive: low, low, nl
Obstructive: low, nl, low
Intrapleural pressure at rest vs between inspiration and expiration
Rest: -5
Between insp and exp: -8
Defective enzyme in PKU
Phenylalanine hydroxylase
Defective enzyme in alkaptonuria
Homogentisate oxidase
Ferric reductase vs ferroxidase
Ferric reductase: Fe3 -> Fe2
Ferroxidase: Fe2 -> Fe3
Two areas that determine frequency vs tidal volume
Frequency: Pre-Botz, PRG
Tidal volume: DRG, VRG
Rostral vs caudal VRG
Rostral: premotor to phrenic
Caudal: premotor to upper airway and expiratory muscles
SARs, RARs, and J receptors: location and what they sense and the effect
SARS: airways, stretch, stop inspiration + prolong inspiration in infants and during exercise
RARs: airways, irritation, cough for protection
J receptors: alveoli, pulmonary edema, tachypnea and dry cough for protein
How long RBC spends in lung, how long O2 requires to reach equilibrium and how long CO2 requires
RBC in lung: 0.75 sec
O2 requires: 0.25 sec
CO2 requires: almost immediate
The negative startling force in the lungs and why
Tissue hydrostatic pressure - bc negative intrapleural pressure
DCs produce which cytokines to stimulate Th17 vs Th1 production?
Th17: IL-1, 6, TGF-B
Th1: IL-12
Hyperacute, acute, and chronic HVGD mechanisms
Hyperacute: pre-formed Abs
Acute: direct allorecognition
Chronic: indirect allorecognition
Order of the tubules of the kidney
Proximal convoluted -> prox straight -> thin loop of Henle -> distal straight -> distal convoluted -> CDs
Tubule histo: prox and distal vs thin loop of henle
Prox and distal tubules: simple cuboidal
Thin loop of Henle: simple squamous