extra stuff that wasnt on the blue print but apparently will be on the test Flashcards
what is Zollinger ellison syndrome
a gastrin secreting pancreatic tumor
causes increased gastric acid leading to PUD
what is the presentation of zollinger ellison syndrome
- PUD s/s (burning/gnawing pain made better by food)
- diarrhea
- hxof multiple PUD’s that do not resolve with h pylori treatment or H2s
50% of zollinger ellison cases occur with what other disease
MEN 1
(3Ps: pancreatic, pituitary and parathyroid tumor disorder)
what is the diagnostic for zollinger ellison syndrome
- serum gastrin level (extremely high)
- secretin test (will inhibit gastrin in normal, but will stimulate gastrin in ZES
- abdominal CT (shows pancreatic tumor)
what is the tx for zollinger ellison syndrome
- PPI (omeprazole) OR octreotide
- surgical rmoval of tumor. chemo if mets.
what causes umbilical hernias
increased intra-abdominal pressure from:
* obesity
* ascites
* long-term abdominal distention.
pregnancy is huge risk factor
what is encapsulated in an umbilical hernia
fat or omentum BUT bowel can become incarcerated within it.
what is the treatment for umbilical hernias
- if easily reducible -> elective surgery repair
- if bowel incarceration -> immediate surgery
what characterizes esophageal stricture
- aperistalsis
- lower esophageal sphincter dysfunction
- progressive dysphagia
what causes esophageal stricture
- GERD
- erosive esophagitis
what is the clinical presentation of esophageal stricture
- heartburn
- progressive dysphagia (to solids)
- odynophagia
- food impaction
- chest pain
what diagnostics are used in suspected esophageal stricture
- initial = barium swallow
- confrimation = EGD
what would you see on EGD of esophageal stricture
- edema
- cellular infiltrates
- basal cell hyperplasia
- increased type III collagen deposition
what is the treatment for esophageal stricture
mechanical esophageal dilation followed by PPIs
steroid injections if refractory
what is achalasia and what causes it
failure of the lower esophageal sphincter to relax secondary to progressive degeneration of ganglion cells in the myenteric plexus in the esophageal wall
aka just distal narrowing of esophagus
what is the presentation of achalasia
- gradual difficulty in swallowing solids AND liquids
- discomfort/fullness when eating
- regurgitation of food
- weight loss
how do you differentiate the presentation of esophageal stricture and achalasia
achalasia has trouble with liquids AND solids. stricture is only solids.
what is the diagnostic study of choice for achalasia
- initial = barium swallow (birds beak)
- confirmation = esophageal manometry