excretion Flashcards
nitrogenous waste
byproduct of protein/nucleic acid metabolism
ammonia
- small, easy to synthesize, water soluble, toxic!
- released by
- diffusion across gills–freshwater/marine
- lots of dilute urine–freshwater
urea`
- mammals and adult amphibians
- less toxic, conserves water
- excreted in urine
uric acid
- terrestrial arthropiods, birds, reptiles
- reactions convert from ammonia
- non-toxic
- excreted as paste–insoluble
- requires energy
- get rid of nitrogen while losing little water
production of nitrogenous waste relates to
- habitat
- tadpoles/aquatic/bony fishes species excrete amonia (aquatic species)
- mammals/amphibians/cartilaginous fishes excrete urea to lose less water
- uric acid–birds/reptiles in dry habitats
insect excretory systems adaptations
- high sa/v ration so water loss is a threat
- ability to close spiracles minimizes water loss from the tracheae
- wax (cuticle) layer on the insect minimizes evaporative water loss
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open circulatory system
- hemolymph is running through body cavity
- malpighian tubules form filtrate from hemolymph
- this is pre-urine that passes through the hind gut where it is processed and modified before excretion
hindgut selectivity
insects that are osmotically stressed due to water/electrolyte shortage reabsorb electrolytes and filtrate from the hindgut back to the hemolymph, while uric acid remains in the hindgut
insect and vertebrate excretion
- water moves only by osmosis
- osmotic gradients set up by active transport of ions
- formation of filtrate is not selective– same molecules present in hemolymph are present in malpighian tubules
- reabsorption is selective
- protein pumps and channels select certain ions/molecules
- waste molecules do not pass through hindgut membrane
- reabsorption is regulated
- membrane pumps and channels are activated/deactivated to respond to osmotic stress
hindgut reabsorption
- H+ pump creates electrochemical gradient in hindgut so K+ can move back into cell–active
- Cl- is moved in via H+/Cl- symporter
- Na+/K+-ATPase pumps Na+ into hemolymph and Na+ flows out of hindgut from high to low
- Cl- and K+ move into hemolymph from high to low
- H2O moves as well in response
where does human excretion occur
kidney
nephron
- basic functional unit of the kidney
- maintains water and electrolyte ballance
Filtration
- renal corpuscle filters blood–size selective
- no cells or proteins exit blood
- passive–blood pressure causes the force to push fluid through filter from closed circulatory system
glomerus
cluster of capillaries that bring blud to the nephron from the renal artery
bowman’s capsule
region of nephron that surrounds the glomerus
renal corpuscle
glomerus and bowman’s capsule
proximal tubule
filtrate leaves bowman’s capsule and enters proximal tubule to start reabsorption
reapsorption active transport
- occurs in epithelial cells
- microvilli expand the SA and provides space for proteins to act as pumps
- exiting pre-urine isotonic to blood
ion and water movement for reabsorption
- na+/K+ atpase removes na+ from interior of cell and creates a gradient for entry of NA+ from lumen
- apical membrane, na+ dependent cotransporters use this gradient to remove vitamins, cl-, and glucose selectively from the filtrate
- solutes diffuse across basolateral membrane into interstitial fluid and blood vessels
- water follows the movement of ions through aquaporin
- whole process selectively retrieves important nutrients
loop of henle
- uses osmotic gradient
- fluid down the descending limb loses water to interstitial fluid surrounding nephron, b/c descending limb is permeable to water
- fluid inside nephron loses Na+ and Cl- passively along concentration gradients in thin ascending limb
- additional Na+ and Cl- ions actively transported out of nephron in thick ascending limb
- exiting pre urine hypotonic to blood
vasa recta
- network of blood vessels that runs along loop and joins with small veins in kidney
- water and salt that move out of the loop of henle diffuse into this
distal tubule/collecting duct
- additional reabsorption occurs
- urine formation and reabsorption is regulated by hormones
aldosterone
- activation of sodium-potassium pumps and reabbsorption of Na+ in distal tubule
- water follows by osmosis
- aldosterone saves sodium and water
ADH
- saves water
- triggers insertion of aquaporins into apical membrane, making it more permeable to water and leads to reaabsorption
- increaes permeability to urea, which is reabsorbed
- creates a concentration gradient favoring reabsorption of water from filtrate