excretion Flashcards

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1
Q

Compare and contrast excretion and secretion

A

Excretion - harmful substance. (urea,co2,bile pigments)
Secretion - useful product (hormone enzymes)
both require ATP

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2
Q

how are excess proteins turned into urea

A

converted into amino acids
undergo deamination - making ammonia
through the ornithine cycle makes urea

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3
Q

what does the PCT reabsorb

A

All glucose and amino acids
some inorganic ions
water - based on bodies needs

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4
Q

how is the PCT adapted for its function

A

Highly folded microvilli are present to increase surface area

Many co transporters - facilitated diffusion of sodium ions, larger glucose ions

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5
Q

at what part of the nephron are the walls impermeable to water

A

Ascending limb

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6
Q

How does the Loop of Henle produce urine

A

Lowers Ψ in order to make a Ψ gradient.
descending limb: water moves out as its permeable to water. ( ions aren’t permeable.)
ascending limb :active transport of ions out (impermeable to water.)
lower Ψ outside of collecting duct then inside so water moves in - making urine.

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7
Q

explain the process of ultrafiltration

A

Afferent arteriole is wider then the efferent arteriole
high hydrostatic pressure is made
liquid is forced put through the fenestration’s in the endothelium.
Basement membrane stops large substances passing through
podocytes are finger like projections allowing for further filtering

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8
Q

what are aquaporins

A

Aquaporins are channels in the cell surface membrane that allow water molecules to pass through

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9
Q

Explain how the stick detects this pregnancy hormone.

A

hcg can pass into the filtrate int he bowman’s capsule
monoclonal antibodies on the stick are complimentary to the hcg
antibodies are attached to a dye which appear when you are pregnant

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10
Q

Suggest why a high intake of protein in the diet will be likely to result in a high concentration of urea in urine.

A

many amino acids which cant be stored in the body , are converted into urea via deamination - making ammonia - then the orthine cycle produces urea . which is cannot be stored int he body for too long and is then excreted out from the body in the urine.

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11
Q

Define excretion

A

removal of metabolic waste from the body

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12
Q

Why do we have to remove waste products from the body

A

so waste products dont build up and inhibit enzyme activity
to maintain blood concentration substances

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13
Q

Name 3 waste products

A

Co2
Nitrogenous compounds - urea
Bile pigments - broken down haemoglobin

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14
Q

What’s the function of the Hepatic artery

A

oxygenated blood supplied to the hepathocytes

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15
Q

What’s the function of the Central Vein

A

takes deoxygenated blood away from the liver

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16
Q

What’s the function of the hepatic portal vein

A

takes deoxygenated blood from the digestive system

17
Q

What may the hepatic portal vein have

A

toxic compounds

18
Q

What’s the function of the sinusoid

A

Where blood from the hepatic artery and hepatic portal vein mix
this increases oxygen concentration

19
Q

What’s the function of the kupffer cells

A

act as macrophages - injest foreign materials

20
Q

What’s the function of the hepathocytes

A

secrete bile into the bile caniculi

21
Q

What’s the function of the bile caniculi

A

where bile is drained into and is transported into the gall bladder

22
Q

Outline 3 functions of the liver

A
  1. store glycogen - when insulin levels rise
  2. detoxification - enzymes break down harmful substrates
  3. Forming urea
23
Q

How is urea formed in the liver

A

Amino acids deaminate and form ammonia and a keto acid . Amino group gets removed

Ammonia gets used in the ornithine cycle and gets converted into urea.
Keto acid is used in respiration