Exam V: Drugs of Abuse

Question 1

Definitions of Addiction, Dependence, Tolerance, and Withdrawal

Answer 1

Addiction: organism engages in compulsive and reinforcing/rewarding behavior, but loses control of limiting intake

Dependence: when an organism normally only in the presence of the drug, and a physical disturbance manifests when drug is removed (withdrawal)

Tolerance: when an organism no longer responds to a drug, and must have higher doses to obtain effectiveness

Question 2

Which area of the brain does cocaine bind that causes pacing, nail biting, and scratching?

Answer 2

Caudate nucleus

Question 3

10 mg IV morphine every 3 hours is equivalent to how much methadone?

Answer 3

10 mg IV methadone every 6 hours

Question 4

Mydriasis is a short term pharmacological affect of which drug?

Answer 4

Morphine

Question 5

Patient comes to ER with narcotic overdose. Which drug do you give them?

Answer 5

Naxolone

Question 6

What is a naturally occurring opiate analgesic-like substances in the brain?

Answer 6

Endorphins

Question 7

Morphine exerts analgesic action on which type of receptors?

Answer 7

Mu

Question 8

Meperidine affects which type of receptors in the limbic system?

Answer 8

Sigma

Question 9

5 mg IV heroine is equivalent to how much methadone?

Answer 9

20 mg oral methadone

Question 10

VTA neurons contain what NT?

Answer 10

Dopamine