Exam Two - RCT Part Two Flashcards
RCTs are level:
1b and 2b
what does PEDro score?
internal validity
how many questions does PEDro have? What is it scored out of? What does a higher score mean?
11
scored out of 10
higher score means greater internal validity
What is considered a good PEDro score for this class?
greater than or equal to 6
1
eligibility criteria was specified
* this question doesn’t get actual points
2
subjective were randomly allocated to groups
“random number generator”
3
allocation was concealed
“opaque, nontranslucent, numbered envelopes”
4
the groups were similar at baseline regarding the most important prognostic indicators
(was random assignment effective??)
5
there was blinding of all subjects
(must be blind at all points)
6
there was blinding of all therapists who administered therapy
(must be blind at all points)
*very difficult to do
7
there was blinding of all assessors who measured at least one key outcome
(must be blind at all points)
8
measures of al least one key outcome were obtained from more than 85% of the subjects initially allocated to groups
- addresses potential loss of stat power and survivorship bias
- if several follow up time points, only required at one of the post tests
10
results of between-group stats comparisons are reported for at least one key outcome
(could be between two different groups or a pre/post test)
9
bonus points for NO drop outs
If no dropouts, you still get point if you used ITT analysis
11
study provides both point measures and measures of variability for a least one key outcome
- average & SD most common. probs provided via graph
survivorship bias
you stay in the study because you’re doing well
is a p value required for a between group comparison?
no
what could you use instead of a P value for a between group comparison?
confidence interval AND
- between group mean diff
- diff in proportions
- number needed to treat
- relative risk
In PEDro, what is the mean score? how many article are a 6 or above?
5.2
40%
what are the most common missing elements in PEDro?
1 - blind therapist
2 - blind subjects
3 - ITT analysis
blind assessors and concealed allocation tied for 4th
does PEDro sub for your critical appraisal?
no
does PEDro recognize inappropriate stats?
no
does PEDro establish clinical relevance/magnitude of effect
no
does PEDro evaluate for external validity
no