Exam One - Sampling in PT literature Flashcards
Generalization
process of drawing conclusions (that apply to all) from a small number of observations
population
larger group to which results are generalized
sample
a subgroup of the population used for estimating characteristics of that population
inclusion criteria
description of the traits that qualify someone to be a subject
to whom can we generalize these results to?
exclusion criteria
description of factors that preclude participation
factors are generally confounding to the results
What is the value of inclusion and exclusion criteria?
- define your population
- limit the influence of confounding subject characteristics
efficacy
very strict inclusion and exclusion criteria minimize selection bias and increase your ability to make cause/effect conclusions
efficacy trials =
high control, limited bias
effectiveness
less strict inclusion and exclusion criteria. increase risk for bias, limit control, and offer less confidence in cause/effect conclusions
effectiveness trials
limited control, greater bias
probability sampling
randomization involved at some point in the process
non-probability sampling
no randomization
must question ability to generalize
far more common in clinical research
What are the main types of probability sampling
- simple random sampling
- systematic sampling
- stratified sampling
- cluster sampling
simple random sampling
each member of the population of interest is equally likely to be selected
(requires entire pop to be known)
systematic sampling
participants chosen from a list (every Kth name)
no independent chance of being selected
need a list of the entire population
stratified sampling
limits sampling error associated with pure random sampling b/c its possible to randomly over/undersample on some key variable
- random sampling from subgroups
cluster sampling
divide pop into clusters, randomly sample clusters, measure all units within sampled clusters and then extrapolate to entire population
What are some types of nonprobability sampling
1 - convenience sampling
2 - quota sampling
convenience sampling
“they are there” very common
- subjects chosen based on availability
- subjects typically from one clinical site
- volunteers tend to have greater motivation
- enrollment typically as participants become available