Exam Three Flashcards
Functions of blood
transport
Protect
regulate
matrix
plasma
formed elements
Erythrocytes (RBC)
Leukocytes (WBC)
Platelets
Serum
remaining flood after blood clot
Blood Plasma Proteins
albumin
globulin
fibrinogen
Albumin
small, most abundant
buffers ph, blood volume, pressure, and flow
fibrinogen
frame work of a blood clot
viscosity
resistance of flow, bc of cohesion of particles
Osmolarity
molarity of dissolved particles that cannot pass thru blood vessel wall
hemopoiesis
production of blood
erythropoiesis
production of Erythrocytes (RBC)
functions of RBC
devoid internal structures
fermentation of ATP
characteristics of RBC
discoidal cell w a biconcave shape and think rim
cytoplasm of hemoglobin
hemoglobin carry how many oxygen
4
most common measurements
hematocrit
hemoglobin concentation
RBC count
RBC life cycle
live 120 days- produce 1mil/sec
reduction in cell size
increase in cell number
synthesis of hemoglobin
loss of nucleus and organelles
primary polycythemia
due to cancer of erythropoietic line of the red bone marrow
RBC counts 11 million
secondary polycythemia
all other causes (dehydration, high altitudes, exercise)
RBC counts 6-8 million
anemia
deficiency of RBCs
result–kidney failure
non nutritional anemia
hypoplastic anemia decline in erythropoiesis
aplastic anemia
cessation of erythropoiesis leads to tissue necrosis and blackening of skin
deadly if not treated
nutritional anemia
iron deficiency anemia
most common
pernicious anemia
deficiency of B12
rare, but not vegetarians
old age– stomach deterioration
sickle cell disease
hereditary hemoglobin defect
Africa
recessive allel modifies hemoglobin
antigen
molecules that are unique to everyone (except twins)
antibodies
proteins created by immune system as response to foreign matter
WBCs characteristics
least
nuclei stain purple
retain organelles thru out life
types of WBCs
granulocytes
Agranulocytes
leukopenia
low WBC count
lead, arsenic, and mercury poisoning
leukocytosis
high WBC count
indicated infection, allergy, or disease
leukemia
cancer of hemopoietic tissue, high amounts of WBCs
myeloid leukemia
uncontrolled granulocyte production
Leukopoiesis
forming of WBCs in bone marrow in adult bones and hematopoietic organs on fetus
acute
appears suddenly
chronic
develops slowly
hemostasis
cessation of bleeding
platelet functions
secret vasoconstrictors
form platelet plugs
initiate clot dissolving enzymes
internalize and destroy bacteria
thrombocytopenia
formation of platelets
3 homeostasis mechanisms
vascular spasm
platelet plug formation
coagulation
vascular spasm
prompt constriction of broken blood vessel
platelet plug formation
platelets adhere to vessel creating a mass that reduces or stops bleeding
coagulation
clotting of blood
fibrinolysis
dissolution of clot
controls to prevent inappropriate clotting
platelet repulsion
dilution
anticoagulants
hemophilia
hereditary diseases characterized by deficiency of a factor
hemophilia missing
A B C
A missing 8
B missing 9
C missing 11
thrombosis
unwanted blood clotting in an uninjured vessel
2 divisions of cardiovascular system
pulmonary circuit
systemic circuit
pulmonary circuit
carries blood to lungs for gas exchange & returns it to the heart
supplied by right half of heart
Systemic circuit
supplies blood to every organ of the body
supplied by left side of heart
pericardium
double walled sac that encloses the heart
three layers of the heart
epicardoum
myocardium
endocardium
epicardium
serous membrane covering heart
inner layer
myocardium
preforms work of the heart
spiral formation
heart chambers
2 superior
*right & left atria
2 inferior
* right & left ventricles
angina pectoris
sense of heaviness or pain in chest
myocardial infraction
sudden death of patch of myocardium, long term obstruction of coronary circulation
cardiocytes
striated short, thick cells
on nucleus
gap junction allows ion to flow between cells
autorhythmic
repair cells , fibrosis
conduction system
coordinates heartbeat
internal pacemaker and conduction pathways
process of conduction system
SA node (pacemaker) initiates each heartbeat & determines the rate
signals travel from SA node throughout atria
AV node sends signals to ventricles down apex
systole
contraction
diastole
relaxation
sinus rhythm
normal heartbeat triggered by SA node
ectopic focus
any region of spontaneous firing NOT caused by SA node
nodal rhythm
spontaneous firing from AV node
arrhythmias
any abnormal cardiac rhythm
atrial flutter
ectopic focus in the atria that set off extra contractions
premature ventricle contraction
Singles or bursts as a result of early firing of an ectopic focus
Ventricle Fibrillation
electrical signals diff places diff times
Defibrillation
emergency procedure
heart is given strong electrical shock in hopes of depolarizing the myocardium and stopping fibrillation
parts of an EKG
P wave
QRS complex
ST segment
T wave
P wave
SA node fires, atria depolarize and contract
QRS complex
ventricular depolarization
spike
ST segment
Ventricle Systole
plateau in myocardial action potential
T wave
Ventricle repolarization and relaxation
Valvular
cusps stiffened, opening constricted by scar tissue
overworked heart
heart murmur
abnormal heart sounds, backward flow of blood
mitral valve proplapse
insufficiency
cusps bulge into atria during contraction
phases of cardiac cycle
isovolumetric contraction
isovolumetric relaxation
ventricular ejection
ventricular filling
ventricular filling
diastole
ventricles expand
pressure drops
AV valves open
blood flows to ventricles
isovolumetric contraction
atria repolarixe and relax, remain in diastole for rest of cardiac cycle
ventricles depolarize, create QRS complex n contract
ventricular ejection
ventricular pressure forces
semilunar valves open
creating plateau and t waves
isovolumetric relaxation
diastole
T wave ends ,ventricles expand
cardiac output
amount of blood ejected by each ventricle in 1 minute
CO= heart rate X stroke volume
Cardiac reserve
difference between the maximum and resting cardiac output
tachycardia
persistence, resting adult hear rate about 100 bmp
bradycardia
persistence, resting adult heart rate below 60 bpm
stroke volume
amount of blood ejected by 1 ventricle w each beat
stroke volume variables
perload
contractility
afterload
preload
amount of tension in ventricular myocardium before contraction
contractility
how hard the myocardium contracts from preload
afterload
sum of all forces opposing ejection of blood from ventricles