Exam III-Mutations Flashcards
Mutagens cause…
An increase in the base rate of mutations by either interacting with DNA and altering the template or physically getting in the way of normal replication.
Caused by specific agents called mutagens
Induced mutations
Categories of mutagens
Chemical and radiation
Categories of chemical mutagens
Analogs
Reactive
Interactive
Categories of radiation mutagens
Ultraviolet
Ionizing
Chemical type of mutagen that is a substitute for normal bases
Analogs
Add alkyl groups to the ring causing the altering of complementarity
Alkylating agents
Flat, Tri-ring planar molecules that have similar molecular dimensions as a base pair that will stack between adjacent base pairs
Intercalating agents
Formation of covalent bonds between itself and it’s neighbor
Dimerization
