Exam 6

Question 1

What are the functions of the urinary system

Answer 1

• Excretion of metabolic wastes, toxins and drugs from the body
• Regulate volume and chemical makeup of blood
• Help regulate blood pressure and kidney function through secretion of enzyme renin
• Help control rate of RBC production by secreting EPO
• Metabolize Vitamin D to its active form

Question 2

What are the layers of the bowman’s capsule

Answer 2

• Visceral layer (podocytes)
• Parietal layer (simple squamous epithelium

Question 3

What is the difference between he afferent and efferent arteriole and how does this play a role in net filtration pressure

Answer 3

The afferent arteriole is bigger which brings in more blood than the efferent arteriole can drain this creates a very high pressure of about 50 - 55mgHg in the glomerulus

This high pressure is required for filtration

Question 4

What are the 3 mechanism that control the GFR

Answer 4

• Autoregulation (myogenic response)
• Tubuloglomerular feedback
• Renin

Question 5

Describe the JG complex the structures involved and what is secreted there

Answer 5

The JG complex is composed of
- Juxtaglomerular cells
- Macula Densa cells
- Extraglomerular cells

JG are baroreceptors cells and secrete renin