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Pharmacology > Exam 5- THE BIG ONE....AUTONOMICS part 3 > Flashcards

Exam 5- THE BIG ONE....AUTONOMICS part 3 Flashcards

1
Q

Some popular Adrenergic Agonists…_______ for asthma (I’ll give you asthma)

A

Al-bu-ter-ol (Proventil, Ventolin, ProAir HFA)

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2
Q

Some popular Adrenergic Agonists…_______ for asthma (I’ll give you asthma)

A

Al-bu-ter-ol (Proventil, Ventolin, ProAir HFA)

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3
Q

Some popular Adrenergic Agonists…________ for ADHD & narcolepsy,

A

Amphetamines (Ritalin, Cylert) for ADHD and for narcolepsy

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4
Q

Some popular Adrenergic Agonists…_______ and alpha-2 agonist for hypertension,

A

CLON-id-ine (Catapres, Duraclon) - alpha2: txmt of hypertension

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5
Q

Some popular Adrenergic Agonists…_______ for treatment of shock and to increase blood flow to kidneys, brain and coronary arteries

A

Dopamine (treatment of shock and increase blood flow to kidneys, brain and coronary arteries)

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6
Q

Some popular Adrenergic Agonists…_______ for colds!

A

Pseudo-ephedrine (Sudafed)

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7
Q

Some popular Adrenergic Agonists…_________ (in Visine eyedrops) – “gets the red out”

A

Tetra-hydro-zo-line

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8
Q

Albuterol is a ______ adrenergic agonist, and therefor it is a potent broncho_______.

A

beta-2….bronchodilator

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9
Q

ANOTHER ONE FOR THE DENTAL OFFICE EMERGENCY KIT!-______ for acute asthma attacks!

A

al-bu-ter-ol

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10
Q

These Adrenergic Agonist side effects are from the shut down of the GI/GU tracts.

A

Constipation and urinary retention

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11
Q

Which andrenergic receptor am I antagonizing?: Block vasoconstriction in skin, Decrease total peripheral resistance, Decrease blood pressure, Reverse dilation of pupils

A

Alpha receptor Antagonists

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12
Q

Adrenergic Agonist side effects- what effect does this have on the heart?

A

Tachycardia (cardiac arrhythmias)

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13
Q

Which andrenergic receptor am I antagonizing? (haha not really a word, more like stimulating): Block vasoconstriction in skin, Decrease total peripheral resistance, Decrease blood pressure, Reverse dilation of pupils

A

Alpha receptor Antagonists

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14
Q

Alpha Antagonisits-Block _________ in skin

A

vasoconstriction

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15
Q

Alpha Antagonists-________ total peripheral resistance

A

decrease

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16
Q

Alpha Antagonists-________ blood pressure

A

decrease

17
Q

Alpha Antagonists-Reverse _______ of pupils

A

dilation

18
Q

Second line agents for the treatment of hypertension…

A

Alpha Antagonists (block vasoconstriction, decrease peripheral resistance, decrease BP)

19
Q

Treatment of peripheral vascular disease (e.g. Raynaud’s syndrome)

A

Alpha Antagonists (Raynaud’s syndrome is coldness in the extremities)

20
Q

What can we use for the diagnosis and treatment of pheochromocytoma (tumor of adrenal medulla that secretes epinephrine)??

A

An alpha Antagonist!

21
Q

WHAT IS THE MAIN INDICATION for the use of an alpha antagonist?

A

Treatment of benign prostatic hypertrophy (make it easier for men with this condition to urinate)!!!

22
Q

Beta Antagoinists show most of their effect on which area of the body?

A

heart and blood vessels

23
Q

Which ones are most used in the US, selective Beta blockers or non-selective?

A

selective Beta-1 blockers- Greater actions on the heart and blood vessels, FEWER side effects, FEWER drug interactions

24
Q

So a non-selective blocker is also going to block Beta-2 receptors which are found in the ______.

A

lungs (causing no bronchodilation)

25
Q

Beta Blockers-_____ heart rate; ______ contractility,

cardiac output and conduction velocity

A

slows..decreases

26
Q

Beta blockers-Decreases cardiac muscle oxygen demand and therefor relieves _______.

A

angina

27
Q

Beta blockers- Popular drugs for the treatment of _______ (often used with diuretics)

A

hypertension

28
Q

Beta Blockers can also treat ________ because they stop tremors and heart palpitations caused by
Grave’s disease or thyrotoxicosis

A

Hyperthyroidism

29
Q

Huh, beta blockers can also help treat _________, because they stop tremors associated with disease.

A

Parkinson’s disease

30
Q

DID YOU KNOW…Beta Blockers can help treat ______ because they reduce intraocular pressure

A

Glaucoma

31
Q

What do all Beta-Antagonists end in?

A

“LOL”-thats not funny

32
Q

What are the two SELECTIVE beta antagonists?

A

aten-o-lol & met-o-pro-lol

33
Q

What are the 3 non-selective beta antagonists?

A

pro-pran-o-lol, nad-o-lol, tim-o-lol (eye med)

34
Q

DENTAL DRUG INTERACTION!!! When patients taking ________ beta blockers (e.g. propranolol) and are given epinephrine, they have a 2 to 4 fold increase in the pressor response to epinephrine: to they get ________ and reflex ________.

A

NON-SELECTIVE…hypertension (increase risk for MI and stroke) and reflex bradycardia

35
Q

DENTAL DRUG INTERACTION!!! When a patient is on a non-selective beta-blocker, we are going to limit the dose of epinephrine in our anesthetic to ____ mg, which is ___ cartridges of anesthetic.

A

0.04 mg….2 cartridges

Pharmacology (23 decks)

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