Exam 5- THE BIG ONE....AUTONOMICS part 3

Question 1

Some popular Adrenergic Agonists…_______ for asthma (I’ll give you asthma)

Answer 1

Al-bu-ter-ol (Proventil, Ventolin, ProAir HFA)

Question 2

Some popular Adrenergic Agonists…_______ for asthma (I’ll give you asthma)

Answer 2

Al-bu-ter-ol (Proventil, Ventolin, ProAir HFA)

Question 3

Some popular Adrenergic Agonists…________ for ADHD & narcolepsy,

Answer 3

Amphetamines (Ritalin, Cylert) for ADHD and for narcolepsy

Question 4

Some popular Adrenergic Agonists…_______ and alpha-2 agonist for hypertension,

Answer 4

CLON-id-ine (Catapres, Duraclon) - alpha2: txmt of hypertension

Question 5

Some popular Adrenergic Agonists…_______ for treatment of shock and to increase blood flow to kidneys, brain and coronary arteries

Answer 5

Dopamine (treatment of shock and increase blood flow to kidneys, brain and coronary arteries)

Question 6

Some popular Adrenergic Agonists…_______ for colds!

Answer 6

Pseudo-ephedrine (Sudafed)

Question 7

Some popular Adrenergic Agonists…_________ (in Visine eyedrops) – “gets the red out”

Answer 7

Tetra-hydro-zo-line

Question 8

Albuterol is a ______ adrenergic agonist, and therefor it is a potent broncho_______.

Answer 8

beta-2….bronchodilator

Question 9

ANOTHER ONE FOR THE DENTAL OFFICE EMERGENCY KIT!-______ for acute asthma attacks!

Answer 9

al-bu-ter-ol

Question 10

These Adrenergic Agonist side effects are from the shut down of the GI/GU tracts.

Answer 10

Constipation and urinary retention

Question 11

Which andrenergic receptor am I antagonizing?: Block vasoconstriction in skin, Decrease total peripheral resistance, Decrease blood pressure, Reverse dilation of pupils

Answer 11

Alpha receptor Antagonists

Question 12

Adrenergic Agonist side effects- what effect does this have on the heart?

Answer 12

Tachycardia (cardiac arrhythmias)

Question 13

Which andrenergic receptor am I antagonizing? (haha not really a word, more like stimulating): Block vasoconstriction in skin, Decrease total peripheral resistance, Decrease blood pressure, Reverse dilation of pupils

Answer 13

Alpha receptor Antagonists

Question 14

Alpha Antagonisits-Block _________ in skin

Answer 14

vasoconstriction

Question 15

Alpha Antagonists-________ total peripheral resistance

Answer 15

decrease

Question 16

Alpha Antagonists-________ blood pressure

Answer 16

decrease

Question 17

Alpha Antagonists-Reverse _______ of pupils

Answer 17

dilation

Question 18

Second line agents for the treatment of hypertension…

Answer 18

Alpha Antagonists (block vasoconstriction, decrease peripheral resistance, decrease BP)

Question 19

Treatment of peripheral vascular disease (e.g. Raynaud’s syndrome)

Answer 19

Alpha Antagonists (Raynaud’s syndrome is coldness in the extremities)

Question 20

What can we use for the diagnosis and treatment of pheochromocytoma (tumor of adrenal medulla that secretes epinephrine)??

Answer 20

An alpha Antagonist!

Question 21

WHAT IS THE MAIN INDICATION for the use of an alpha antagonist?

Answer 21

Treatment of benign prostatic hypertrophy (make it easier for men with this condition to urinate)!!!

Question 22

Beta Antagoinists show most of their effect on which area of the body?

Answer 22

heart and blood vessels

Question 23

Which ones are most used in the US, selective Beta blockers or non-selective?

Answer 23

selective Beta-1 blockers- Greater actions on the heart and blood vessels, FEWER side effects, FEWER drug interactions

Question 24

So a non-selective blocker is also going to block Beta-2 receptors which are found in the ______.

Answer 24

lungs (causing no bronchodilation)

Question 25

Beta Blockers-_____ heart rate; ______ contractility, | cardiac output and conduction velocity

Answer 25

slows..decreases

Question 26

Beta blockers-Decreases cardiac muscle oxygen demand and therefor relieves _______.

Answer 26

angina

Question 27

Beta blockers- Popular drugs for the treatment of _______ (often used with diuretics)

Answer 27

hypertension

Question 28

Beta Blockers can also treat ________ because they stop tremors and heart palpitations caused by Grave’s disease or thyrotoxicosis

Answer 28

Hyperthyroidism

Question 29

Huh, beta blockers can also help treat _________, because they stop tremors associated with disease.

Answer 29

Parkinson’s disease

Question 30

DID YOU KNOW...Beta Blockers can help treat ______ because they reduce intraocular pressure

Answer 30

Glaucoma

Question 31

What do all Beta-Antagonists end in?

Answer 31

"LOL"-thats not funny

Question 32

What are the two SELECTIVE beta antagonists?

Answer 32

aten-o-lol & met-o-pro-lol

Question 33

What are the 3 non-selective beta antagonists?

Answer 33

pro-pran-o-lol, nad-o-lol, tim-o-lol (eye med)

Question 34

DENTAL DRUG INTERACTION!!! When patients taking ________ beta blockers (e.g. propranolol) and are given epinephrine, they have a 2 to 4 fold increase in the pressor response to epinephrine: to they get ________ and reflex ________.

Answer 34

NON-SELECTIVE...hypertension (increase risk for MI and stroke) and reflex bradycardia

Question 35

DENTAL DRUG INTERACTION!!! When a patient is on a non-selective beta-blocker, we are going to limit the dose of epinephrine in our anesthetic to ____ mg, which is ___ cartridges of anesthetic.

Answer 35

0.04 mg....2 cartridges