Exam 2: Antibiotics-Quinolones, Metronidazole, Misc, AminoGlycosides Flashcards
What class of antibiotics is our BIG GUN? Cleans out the garage by BLOWING it up
Quniolones
What is the mechanism of action of Quinolones? Spectrum? Cidal/Static?
Inhibit DNA synthesis during bacterial replication..broad spectrum, bacteriocidal
What is the sub category of Quinolones?
FluoroQuniolones
What is the primary antibiotic given to Anthrax exposure?
CiproFloxacin
What is the target for Ciprofloxaxin?
DNA Topoisomerases (busts replication, transcription, and repair. BOOM BITCH)
What is a major oral adverse event of Quniolones?
Xerostomia!
Qunolones are the first drug to have this type of adverse effect…
CNS! Dizziness, headache, vertigo
What class am I? Medical = to treat resistant organisms
Quniolones
What are the two Quniolones that we need to know?
CiproFloxacin and LevoFloxacin
What class of drugs is antibiotic, amebicide, antiprotozoal Bactericidal, Broad spectrum, and is a Synthetic drug??
Metro-Ni-Da-Zole
Metronidazole: Used to supplement other antibiotics when _________ condition is not responding…Broadens spectrum of kill when used in combination….Not susceptible to ________…Very effective against periodontal pathogens*
periodontal…penicllinase
KNOW THESE!! What are the 4 adverse effects of MetroNiDazole?
1.Hematopoietic System 2.Metallic Taste 3.Circumoral Paresthesia 4.Oral Ulcerations
Which drug do you ESPECIALLY want to avoid alcohol when using? SO NO EtOH MOUTHWASH!!!! It is a “_______” like reaction.
Metro-ni-dazole..”disulfram” like rxn
What is the mechanism of action of Vancomycin?
Inhibits bacterial cell wall synthesis (diff from penicillin tho)
Vancomycin (Vancocin) “________” antibiotic, Inhibits _______ synthesis, but with a different mechanism than the penicillins…Used for ______ staph infections, strep infections, enterococcal infections…Used to treat antibiotic-induced pseudomembranous colitis caused by _____.


“miscellaneous”…bacterial cell wall..resistant…C/ Diff
