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0 Pharmacology > Exam 5 Deck 8 > Flashcards

Exam 5 Deck 8 Flashcards

1
Q

Drug to promote cellular growth

A

Somatotropin

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2
Q

Drug to reduce growth hormone

A

Octreotide

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3
Q

AE: somatotropin

A

Hyperglycemia

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4
Q

AE Octrotide

A

Glucose dysregulation, GI upset

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5
Q

Drug for reabsorbing water

A

Desmopressin

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6
Q

Indication for Desmopressin

A

Diabetes insipidus, bed wetting (von willlerbrand’s)

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7
Q

Indications for Octreotide

A

Tumor with growth hormone, other excessive GH

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8
Q

AE of Desmopressin

A

Hyponateriam
(Water dilution inside

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9
Q

Drug for thyroid hormone replacement

A

Levothyroxine
Treats hypothyroidism
Can cause hyperthyroidsim

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10
Q

Indication to increase dose of levothyroxine

A

Elevated TSH

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11
Q

Contra Indication for levothyroxine

A

Cardiovascular disease

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12
Q

Drug to lower thyroid activity (Treat Grave’s disease)

A

Methimazole

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13
Q

CI for methimazole

A

Immunocompromised

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14
Q

Indication for Propythiouracil

A

Hyperthyroidism

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15
Q

How Propylthiouracil prevents Thyroid stimulations

A

Prevents Iodine from being active

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16
Q

Drugs to treat addisons disease

A

Hydrocortisone and Fludrocortisone

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17
Q

MOA and AE of hydrocortisone

A

MOA: Gucocorticoid
AE: Cushing’s syndrome, Infection, glucose intolerance, osteoporosis, adrenal suppression, peptic ulcers

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18
Q

MOA of fludrocortisone

A

Mineralcorticoid: promotes Na+ reabsorption
K+ and H+ excretion

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19
Q

S/S of hypoglycemia

A

Sweating
Pallor
Hunger
Irritability
Lack of coordination
Sleepy
(Hangry)

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20
Q

S/S of hyperglycemai

A

(Dry)
Dry mouth
Thirst
Headache
Blurred vision

Frequent urination
Weakness

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21
Q

Normal range for serum glucose

A

70-110 mg/dL

22
Q

Test to measure 3 month glucose level

23
Q

LeARNinG(D)
Pneumonic

A

Rapid acting
Lispro, Aspart

Short acting
Regular (clear)

Intermediate acting
NPH

Long acting Gargine, Detemir

24
Q

Onset for rapid acting insulin (Lispro, Aspart)

25
Q

Onset short acting insulin (Regular)

A

30-60 minutes

26
Q

Onset for intermediate acting insulin (NPH)

A

60-120 min

27
Q

Onset for long acting insulin (Glargine, Detemir)

28
Q

Peak effect for rapid acting insulin (lispro, aspart)

A

30 min - 2.5 hrs

29
Q

Peak affect for short acting insulin (regular)

30
Q

Peak effect for intermediate acting insulin (NPH)

31
Q

Peak effect for long acting insulin (glargine, determir)

32
Q

Duration of action for rapid acting insulin (lispro, aspart)

33
Q

Duration of action of short acting insulin (regular)

34
Q

Duration of action for intermediate acting insulin (NPH)

35
Q

Duration of action for long acting insulin (Glargine, detemir)

36
Q

When to use rapid acting insulin (lispro, aspart)

A

Meals or acute hyperglycemia

37
Q

When to use short acting insulin (regular)

A

Meals/acute hyperglycemia

38
Q

When to use intermediate insulin (NPH)

A

Basal levels

39
Q

When to use long-acting insulin (Glargine, Detemir)

A

Basal insulin

40
Q

Drugs to use in Type II diabetes mellitus

A

Glyburide/glipizide
Repaglinide
Acarbose
Canagliflozin
Metformin

41
Q

When to use glucagon

A

Hypoglycemia, emergency treatment

42
Q

Treatments for Type II DM that can cause hypoglycemia

A

Repaglinide
Glyburide/glipizide

43
Q

Type II DM meds that do not cause Hypoglycemia

A

Metformin
Acarbose
Canagliflozin
Pramlintide

44
Q

Treatment options for Type I DM

45
Q

MOA of met formin

A

Increases glucose uptake through increasing insulin sensitivity

46
Q

Adverse effects of metformin

A

Lactic acidosis
GI upset, VB12 and folate deficiency

47
Q

MOA of glyburide and Repaglinide

A

Stimulates the pancreas to release insulin

48
Q

MOA and AE for Acarbose

A

MOA: Slows carbohydrate absorption
AE: GI upset

49
Q

MOA and AE of Canagliflozin

A

MOA: Causes kidney to excrete glucose
AE: Cystitis, candidiasis, polyuria, hypotension (Increased glucose in urine= more infection)

0 Pharmacology (8 decks)

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