Exam 4 (Week 15) Flashcards

1
Q

Pharmacological class of Beclomethasone (QVAR)

A

glucocorticoid

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2
Q

Therapeutic class of Beclomethasone (QVAR)

A

anti-inflammatory

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3
Q

MOA of Beclomethasone (QVAR)

A
  1. decreases synthesis and release of inflammatory mediators–>decreasing infiltration and activity of inflammatory cells.
  2. decreasing edema of the airway mucosa
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4
Q

What does beclomethasone (QVAR) MOA reduce?

A
  1. bronchial hyperactivity

2. airway mucus production

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5
Q

What is beclomethasone (QVAR) used for?

A
  1. prophylaxis of chronic asthma
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6
Q

Inhaled glucocorticoids or beclomethasone (QVAR) is used for?

A
  1. for the management of inflammatory component of asthma
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7
Q

Oral glucocorticoids or beclomethasone (QVAR) may be used for or in?

A
  1. In patients who have moderate to severe persistent asthma
  2. management of acute exacerbations of asthma
  3. COPD
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8
Q

What are ADES of glucocorticoids dependent on?

A

on route and length of administration

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9
Q

What are 3 ADEs of inhaled beclomethasone (QVAR) or glucocorticoids?

A
  1. adrenal suppression
  2. oral candidacies - thrush
  3. dysphonia - hoarseness or difficulty speaking
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10
Q

What are ADEs of oral beclomethasone (QVAR) or glucocorticoids dependent on? What are 4 adverse effects of oral glucocorticoids or beclomethasone (QVAR)?

A

a. prolonged therapy:
1. adrenal suppression
2. osteoporosis
3. peptic ulcer disease
4. growth suppression

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11
Q

1 nursing implication of beclomethasone (QVAR)?

A

educate patients on how to use inhalation devices

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12
Q

Pharmacological class of cromolyn (intal)?

A

mast cell stabilizer

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13
Q

Therapeutic class of cromolyn (intal)?

A

anti-inflammatory

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14
Q

MOA of cromolyn (intal)?

A

suppresses bronchial inflammation

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15
Q

Uses of cromolyn (intal)?

A

prophylaxis for asthma and COPD, rather than acute treatment

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16
Q

Pharmacological class of albuterol (proventil)?

A

Beta2-adrenergic agonist

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17
Q

Therapeutic class of albuterol (proventil)?

A

Short-acting bronchodilator

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18
Q

MOA of albuterol (proventil)?

A

activates beta2 adrenergic receptors in the smooth muscle of the lung.

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19
Q

Uses of bronchodilators?

A

used to provide symptomatic relief in patients who have asthma and COPD, but does not alter the underlying inflammation that is apart of the disease process.

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20
Q

What does the MOA of albuterol (proventil) promote and relieve?

A
  1. promotes bronchodilation

2. relieves bronchospasm

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21
Q

use of albuterol (proventil)?

A

asthma and COPD

22
Q

what is significant about bronchodilators or albuterol (proventil)?

A

route and time course

23
Q

How can bronchodilators such as albuterol (proventil) be given?

A

orally or by inhalation

24
Q

Bronchodilators given orally or for only what?

A

long term control

25
Q

SABAs (Short-acting) are what? used to stop what?

A

life-saving; use to stop an ongoing attack

26
Q

What are LABAs reserved for? Use for?

A

reserved for patients who experience frequent attack. Long-term control

27
Q

What is the larger classification of albuterol (proventil)?

A

inhaled SABA

28
Q

3ADE of albuterol (proventil):

A
  1. tachycardia
  2. angina
  3. tremor
29
Q

Inhaled LABAs increased the risk for what?

A
  1. severe asthma

2. asthma related death

30
Q

ADE of oral bronchodilators:

A
  1. cardiac adverse effects - angina pectoris, tachydysrythmias, tremors in skeletal muscle
31
Q

1 nursing implication of albuterol (proventil) or bronchodilators:

A

these drugs should be taken on a fixed schedule.

32
Q

Pharmacological class of montelukast (singular):

A

leukotriene antagonist

33
Q

Therapeutic class of montelukast (singular):

A

immune modulator

34
Q

MOA of montelukast (singular):

A

suppress the effects of leukotrienes

35
Q

Uses of montelukast (singular):

A
  1. allergic rhinitis
  2. cough
  3. cold
36
Q

Pharmacological class of dextromethorphan (robitussin):

A

nonopioid antitussive

37
Q

Therapeutic class of dextromethorphan (robitussin):

A

Anti-cough

38
Q

MOA of dextromethorphan (robitussin):

A
  1. opioid derivative that acts in the CNS to suppress the cough reflex
  2. blocks NMDA receptors in the brain and spinal cord
39
Q

What does blocking NMDA receptors in the brain in spinal cord with dextromethorphan (robitussin) do?

A
  1. decreases pain with cough
40
Q

use of dextromethorphan (robitussin):

A
  1. cough that is nonproductive, creates discomfort, or deprives a pt. of comfort or sleep
41
Q

ADEs of dextromethorphan (robitussin) are what? except at what?

A

a. rare

b. high doses

42
Q

ADEs of dextromethorphan (robitussin):

A
  1. mild inebriation to a state of mind-body dissociation
43
Q

1 nursing implication of dextromethorphan (robitussin):

A

take only as prescribed on the label

44
Q

What are 2 routes of administration for respiratory drugs?

A
  1. oral

2. inhalation

45
Q

Inhaled respiratory drugs have minimal what? Relieve what?

A

a. systemic effects

b. relieve acute attacks rapidly

46
Q

What is the age that you should avoid use of OTC cold remedies?

A

younger than 4-6 years old

47
Q

What should the labels say if giving children OTC cold remedies?

A

only for pediatric use

48
Q

Who should you consult before giving OTC cold remedies to children?

A

a provider

49
Q

What should you read before dosing OTC cold remedies to children?

A

labels and product info

50
Q

What should you use to dose OTC cold remedies to children?

A

the provided measuring device

51
Q

What should you do as the parent if a child’s symptoms persist or worsen?

A

discontinue or seek help

52
Q

What can anti-histamines cause in children?

A

cause respiratory depression