Exam 4 (Week 15) Flashcards
Pharmacological class of Beclomethasone (QVAR)
glucocorticoid
Therapeutic class of Beclomethasone (QVAR)
anti-inflammatory
MOA of Beclomethasone (QVAR)
- decreases synthesis and release of inflammatory mediators–>decreasing infiltration and activity of inflammatory cells.
- decreasing edema of the airway mucosa
What does beclomethasone (QVAR) MOA reduce?
- bronchial hyperactivity
2. airway mucus production
What is beclomethasone (QVAR) used for?
- prophylaxis of chronic asthma
Inhaled glucocorticoids or beclomethasone (QVAR) is used for?
- for the management of inflammatory component of asthma
Oral glucocorticoids or beclomethasone (QVAR) may be used for or in?
- In patients who have moderate to severe persistent asthma
- management of acute exacerbations of asthma
- COPD
What are ADES of glucocorticoids dependent on?
on route and length of administration
What are 3 ADEs of inhaled beclomethasone (QVAR) or glucocorticoids?
- adrenal suppression
- oral candidacies - thrush
- dysphonia - hoarseness or difficulty speaking
What are ADEs of oral beclomethasone (QVAR) or glucocorticoids dependent on? What are 4 adverse effects of oral glucocorticoids or beclomethasone (QVAR)?
a. prolonged therapy:
1. adrenal suppression
2. osteoporosis
3. peptic ulcer disease
4. growth suppression
1 nursing implication of beclomethasone (QVAR)?
educate patients on how to use inhalation devices
Pharmacological class of cromolyn (intal)?
mast cell stabilizer
Therapeutic class of cromolyn (intal)?
anti-inflammatory
MOA of cromolyn (intal)?
suppresses bronchial inflammation
Uses of cromolyn (intal)?
prophylaxis for asthma and COPD, rather than acute treatment
Pharmacological class of albuterol (proventil)?
Beta2-adrenergic agonist
Therapeutic class of albuterol (proventil)?
Short-acting bronchodilator
MOA of albuterol (proventil)?
activates beta2 adrenergic receptors in the smooth muscle of the lung.
Uses of bronchodilators?
used to provide symptomatic relief in patients who have asthma and COPD, but does not alter the underlying inflammation that is apart of the disease process.
What does the MOA of albuterol (proventil) promote and relieve?
- promotes bronchodilation
2. relieves bronchospasm