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NURS 472A > Exam 3 (Week 12) > Flashcards

Exam 3 (Week 12) Flashcards

1
Q

What is the brand name of cimetidine?

A

tagamet

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2
Q

Pharmacological class of cimetidine:

A

Histamine2 (H2) receptor antagonist

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3
Q

Therapeutic class of cimetidine:

A

Antiulcer/Drug for Peptic Ulcer Disease (PUD)

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4
Q

MOA of cimetidine:

A

blocking H2 receptors on the parietal cells in the stomach.

2. reduces both the volume of gastric juice and its hydrogen ion concentration.

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5
Q

Uses of cimetidine:

A
  1. treatment of gastric and duodenal ulcers
  2. GERD
  3. zollinger ellison syndrome
    Available over the counter for:
    heartburn, acid indigestion, and sour stomach
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6
Q

ADE of cimetidine:

A
  1. anti-adrenergic effects
  2. CNS effects especially in older adults who have renal or hepatic impairment
  3. pneumonia
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7
Q

1 nursing implication of cimetidine:

A

to promote smoking cessation

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8
Q

What is the brand name of omeprazole?

A

Prilosec

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9
Q

Pharmacological class of omeprazole:

A

proton pump inhibitor (PPI)/prodrug

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10
Q

Therapeutic class of omeprazole:

A

Antiulcer/Drug for PUD

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11
Q

MOA of omeprazole:

A

prodrug

  1. undergoes conversion into its active form within parietal cells in the stomach.
  2. active form causes irreversible inhibition of hydrogen-potassium-ATPase (enzyme that generates gastric acid)
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12
Q

short term uses of omeprazole:

A

Short term therapy of…

  1. duodenal ulcers
  2. gastric ulcers
  3. erosive esophagitis
  4. GERD
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13
Q

long term uses of omeprazole:

A

hypersecretory conditions (zollinger ellison’s syndrome)

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14
Q

ADE of short term use of omeprazole:

A

minor

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15
Q

ADE of long-term use of omeprazole:

A
  1. pneumonia
  2. fractures
  3. re-bound acid hypersectretion
  4. hypomagnesemia
  5. infection with C. diff
  6. gastric cancer
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16
Q

1 nursing implication of omeprazole:

A

informing the patient about signs and symptoms of respiratory infection

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17
Q

What is the brand name of methylcellulose?

A

Citrucel

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18
Q

Pharmacological class of methylcellulose:

A

Bulk-forming laxative

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19
Q

Therapeutic class of methylcellulose:

A

Constipation

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20
Q

What does methylcellulose have the same effect as?

A

The same impact on bowel function as dietary fiber (non-digestible and non-absorbable)

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21
Q

MOA of methylcellulose:

A

The drug swells in water to form a viscous solution softening fecal mass and increasing its bulk.

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22
Q

Uses of methylcellulose:

A

Temporary treatment of constipation

  1. Direticulosis
  2. irritable bowel syndrome
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23
Q

ADE of methylcellulose:

A
  1. esophageal obstruction if the drugs are swallowed in the absence of fluids
  2. intestinal obstruction or impaction (passage through the intestine is impeded)
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24
Q

1 nursing implication of methylcellulose:

A

instruct the patient to take the med with full glass of water or juice

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25
Q

What is the brand name of bisacodyl?

A

Dulcolax

26
Q

Pharmacological class of bisacodyl:

A

stimulant laxative

27
Q

Therapeutic class of bisacodyl:

A

constipation

28
Q

What is important to note about stimulant laxatives?

A

widely used and abused

29
Q

How many effects do stimulant laxatives have on the bowel?

A

2

30
Q

What is the brand name of magnesium hydroxide?

A

milk of magnesia

31
Q

Pharmacological class of magnesium hydroxide:

A

osmotic laxative

32
Q

Therapeutic class of magnesium hydroxide:

A

constipation

33
Q

What is magnesium hydroxide considered?

A

a laxative salt

34
Q

What is the brand name of ondansetron?

A

Zofran

35
Q

Pharmacological class of ondansetron:

A

serotonin receptor antagonist

36
Q

Therapeutic class of ondansetron:

A

antiemetic

37
Q

MOA of ondansetron:

A

blocking type 3 serotonin receptors located in the CTZ and on afferent fagal neurons in the upper GI tract.

38
Q

When is ondansetron more effective?

A

when it is combined with a glucocorticoid

39
Q

Uses of ondansetron:

A

management of chemotherapy induced nausea and vomiting

nausea and vomiting associated with anesthesia, biro gastritis, and morning sickness of pregnancy

40
Q

ADE of ondansetron:

A
  1. headache
  2. diarrhea
  3. dizziness
  4. Prolongnation of QT interval
41
Q

1 nursing implication of ondansetron:

A

monitoring electrolytes

42
Q

What is the brand name of metoclopramide?

A

Reglan

43
Q

Pharmacological class of metoclopramide:

A

Dopamine and serotonin antagonist in chemoreceptor trigger zone (CTZ)/enhances actions of acetylcholine

44
Q

Therapeutic class of metoclopramide:

A

Antiemetic/Prokinetic

45
Q

MOA of metoclopramide:

A
  1. suppresses emesis by blocking receptors for dopamine and serotonin in the CTZ
  2. Increases upper GI motility by enhancing the actions of acetylcholine
46
Q

How can metoclopramide be given?

A

orally or intravenously

47
Q

Uses of oral metoclopramide:

A
  1. diabetic gastroporesis

2. suppression of GERD

48
Q

Uses of intravenous metoclopramide:

A
  1. suppress post-operative nausea and vomiting
  2. suppress chemotherapy induced nausea and vomiting
  3. facilitation of certain GI procedures
49
Q

AE of metoclopramide depend on what?

A

dose

50
Q

AE high dose therapy of metoclopramide:

A
  1. sedation

2. diarrhea

51
Q

AE of long-term high dose therapy of metoclopramide:

A

irreversible tardive dyskinesia

52
Q

1 nursing implication of metoclopramide:

A

educate patient regarding sedative effects

53
Q

What is the brand name of sulfasalazine?

A

Azulfidine

54
Q

Pharmacological class of sulfasalazine:

A

5-aminosalicylate (5-ASA)

55
Q

Therapeutic class of sulfasalazine:

A

Drug for inflammatory bowel disease (IBD)

56
Q

MOA of sulfasalazine:

A

broken down into 5-ASA and sulfa pyrodine

  1. 5-ASA acts by suppressing prostaglandin synthesis and suppressing the migration of inflammatory cells into the infected area.
  2. sulfa pyrodine acts by caused adverse effects.
57
Q

Uses of sulfasalazine:

A
  1. manage acute episodes of mild to moderate ulcerative colitis
  2. crohn’s disease
58
Q

ADE of sulfasalazine:

A
  1. nausea
  2. fever
  3. rash
  4. arthralgia
  5. hematologic disorders
59
Q

1 nursing implication of sulfasalazine:

A

monitor complete blood cell counts

60
Q

What is the brand name of ursodial?

A

actigall

61
Q

Pharmacological class of ursodial:

A

Ursodeoxycholic acid/analog of chenodiol

62
Q

Therapeutic class of ursodial:

A

Drug used to dissolve gallstones

NURS 472A (9 decks)

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