Exam 4 Start: Lecture 16 Flashcards

Population genetics cont.

You may prefer our related Brainscape-certified flashcards:
1
Q

What is the Wahlund Effect?

A

2 or more sub population in HWE but complete pop is not

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How do you solve a problem asking if the Wahlund effect is present?

A

Calculate if ea sub pop is in HWE and if the total pop is in HWE.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the issue that occurs when you don’t account for the Wahlund effect in sub populations?

A

The RMP is lower than the true value.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How can you tell if there is inbreeding present?

A

Excessive homozygous genotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

**What does theta do to your calculations? (How is it with/ without?)(The effect theta has on RMP)

A

Look online/textbook

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

If unsure of the effect of sub populations, genetic variable theta is used. What is theta?

A

It is usually 0.01, a measure of substructure used to adjust the RMP calc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is LR likelihood ratio? What does it do?

A

P of obs the evidence under competing case scenarios.
Allows for subjectivity
compares both scenarios, forced to consider alt hypothesis

How to calc:
P(match given suspect is the source) / P(match given suspect is not the source)

Genetic evidence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Notations for:
- Prosecutors hypothesis
- Defense hypothesis
- Genetic evidence
- All other evidence

A
  • H(subscript p)
  • H(subscript d)
  • E
  • I
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the Odds Form of Bayes Theorem?

A

Write equation in notation and in words
Notation:
P(

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Prior odds

A

you don’t like that guy…. / what made you arrest them in the first place

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Posterior odds

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

If the prosecutors hypothesis is correct

A

the probability = 1 (numerator)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If the defense hypothesis is correct

A

RMP (denominator), so inverse of RMP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What effect does theta have on the answer

A

It makes it larger, and helps the defendant.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly