Exam 4 - Random Stuff Flashcards
when giving GCs for IBD, what two things should we supplement?
calcium 1000-15000 mg/day
vitamin D 800 U/day
T or F: natalizumab should NOT be used in combo w/ immunosuppressants or TNF inhibitors
T (Natalie works alone)
natalizumab is associated with which CNS disorder related to JC infection?
PML
drugs that end in -kizumab are in what class?
IL23 antag
tofacitinib and upadacitinib black box warning
VTE
which of the following drugs are for both UC and CD?
a. tofacitinib
b. upadacitinib
b. upadacitinib
T or F: upadacitinib is CI in pregnancy
T
T or F: ozanimod and estrazimod are CI in pts with cardiac history in last 6 months
T
are ozanimod and estrazimod used for UC, CD, or both?
UC
if you see the term “transmural”, what should we think?
CD
which drug for gout has an AE of urolithiasis?
probenecid
non-pharm thing we can do that helps with gout
applying ice
indomethacin dose for acute gout
a. 50 mg PO TID
b. 750 mg PO followed by 250 mg q8h
c. 400 mg PO TID
d. 200 mg PO BID
a. 50 mg PO TID
naproxen dose for acute gout
a. 50 mg PO TID
b. 750 mg PO followed by 250 mg q8h
c. 400 mg PO TID
d. 200 mg PO BID
b. 750 mg PO followed by 250 mg q8h
ibuprofen dose for acute gout
a. 50 mg PO TID
b. 750 mg PO followed by 250 mg q8h
c. 400 mg PO TID
d. 200 mg PO BID
c. 400 mg PO TID
sulindac dose for acute gout
a. 50 mg PO TID
b. 750 mg PO followed by 250 mg q8h
c. 400 mg PO TID
d. 200 mg PO BID
d. 200 mg PO BID
which corticosteroid formulation for gout can be given intra-articularly?
a. methylprednisolone
b. prednisone
c. triamcinolone
c. triamcinolone
IA triamcinolone dose for large joints (range)
10-40 mg
IA triamcinolone dose for small joints (range)
5-20 mg
prednisone taper: ___ mg/kg daily for ___-___ days, followed by taper for ___-___ days
0.5; 2-5; 7-10
colchicine dosing for acute gout (day 1 and 2+)
day 1: 1.2 mg PO once, then 0.6 mg one hour later
day 2+: 0.6 mg BID until attack resolves
which drug has AEs of axonal neuromyopathy and neutropenia?
a. NSAIDs
b. methylprednisolone
c. probenecid
d. colchicine
d. colchicine
colchicine renal dose adjustments start at CrCl < ___
30
T or F: colchicine needs to be dose adjusted in hepatic impairment
F (only needs adjustment in renal impairment)