Exam 4: Nervous System Flashcards
what is white matter made of
bundles of myelinated axons
neural tracts
-propagation of action potential from one area to the next
what is gray matter made of
bundles of unmyelinated axons
neuron cell bodies & dendrites
-integration and relaying of signals
what is a synapse
junction between two cells in the nervous system
what are the different components of synapses
neuron and effector synapse (muscle or gland)
neuron and neuron synapse
what do pre-synaptic neurons do
send signals (away from CNS)
what do post-synaptic neurons do
receive signals (to CNS)
what are the types of synapses
electrical synapses
chemical synapses
What are electrical synapses
pass electrical signal directly from cytoplasm of one cell to another via gap junctions
-allows rapid bidirectional signal conduction (especially important in the heart)
what are chemical synapses
conducts signals via neurotransmitters
-very common (nervous system uses this communication the most)
Steps of neurotransmitter release
Same as acetylcholine release EXCEPT:
-neurotransmitter binds to receptors on post-synaptic neuron’s dendrite (instead of muscle fiber)
-axon terminal of pre-synaptic neuron synapses to post-synaptic neuron
what do neurotransmitters effect
effects are on target cells (like neurons or muscles) via receptors
how are neurotransmitters classified
based on structure
-except acetylcholine - its in its own category
Describe acetylcholine
neurotransmitter that effects skeletal muscle, autonomic nervous system, smooth & cardiac muscle
-within the CNS
what is acetylcholine secreted by
cholinergic neurons
what does acetylcholine bind to
cholinergic receptors
what are the different neurotransmitters
acetylcholine
monoamines
amino acids
purines
neuropeptides
gases
what are the 2 types of monoamine neurotransmitters
catecholamines
indolamines
what are catecholamines
epinephrine, norepinephrine, dopamine
what are indolamines
serotonin, melatonin
what is a specific amino acid neurotransmitter
GABA - inhibitory (inhibits things)
what is a specific gas neurotransmitter
nitric oxide
what are the responses to neurotransmitters
response of post-synaptic neuron to a neurotransmitter can vary:
-excitatory and inhibitory responses can occur
what does an excitatory post-synaptic potential (EPSP) result in
depolarization (+ charge) of post-synaptic neuron
-due to Na+ (sodium) influx
what does an inhibitory post-synaptic potential (IPSP) result in
hyperpolarization (- charge) of post-synaptic neuron
-due to Cl- (Chloride) influx or excessive K+ (potassium) efflux (leaving cell)
describe summation
-signals from other neurons occur at dendrites
-these are graded potentials (weak stimulus produces a weak response, strong stimulus produces strong response)
-graded potentials summate (total up) at trigger zone
-If threshold (-55 mV) is reached, an action potential will be produced and propagated along axon to axon terminals
——> leads to something like neurotransmitter release
How many major regions exist in the adult brain
4
what are the 4 major regions of the adult brain
- Cerebrum
- Diencephalon
- Brainstem
- Cerebellum
what does each region of the brain contain
nuclei
-clusters of neuron cell bodies in the Central Nervous System (CNS)
what is the cerebrum responsible for
higher brain functions
what does the cerebrum contain
cerebral cortex - layer of gray matter surrounding cerebrum
left & right cerebral hemispheres - separated by longitudinal fissure
how does communication across hemispheres of cerebrum occur
through commissures
-connections across hemispheres
-corpus callosum - biggest commissure
what is the left hemisphere of the brain responsible for
language function
what is the right hemisphere of the brain responsible for
spatial perception, nonverbal reasoning
True or False
-myth of lateralization is oversimplified
true
what are the cortical lobes of the brain
frontal lobe
prefrontal cortex
parietal lobe
occipital lobe
temporal lobe
what are the functions of the frontal lobe
-motor functions
-planning movements and executing movements
what are the functions of the prefrontal cortex
-most anterior portion of the frontal lobe
-associated with personality
-regulation of emotional behavior & mood
-motor decision making
what is the function of the parietal lobe
processing of somatic sensations from body
what is the function of the occipital lobe
visual processing
what are the functions of the temporal lobe
-auditory processing
-regions for memory formation
what are the special functions of the cerebral cortex
-speech
-memory
what is speech
integration of sensory information and generation of words
what areas of the brain make speech possible
Wernicke’s area
-language development
Broca’s area
-word formation
Arcuate Fasiculus
-connects Wernicke’s & Broca’s areas
what is memory
storage of knowledge
what are the different kinds of memory
working memory
short-term memory
long term memory
describe working memory
transient (shorter than short-term memory)
-task associated
describe short-term memory
lasts minutes to day
-susceptible to trauma
describe long-term memory
lasts for years or more
-consolidation (transfer of short-term to long-term memory)
-strengthening of synaptic connections
how are synaptic connections strengthened in long-term memory
-cAMP responsive transcription factor activates transcription for proteins
-dendritic spines - more/stronger synaptic connections
what are the types of long-term memory
declarative
procedural