EXAM 4 Hematopoiesis and Innate Immunity Flashcards
The Immune System physical barriers
skin, epithelial surfaces, cilia
The Immune System chemical barriers
acids, mucous, lysozymes
what is immunity?
the body’s protective reactions to foreign invaders
immunity to self substances is known as
autoimmunity
Immunity is mediated by the collective, coordinated response of ______.
immune cells and the molecules they produce
type of immunity that is In place before infection occurs, nonspecific, quick (minutes to hours)
Innate immunity – “Native” immunity
Innate immunity – “Native” immunity
In place before infection occurs, nonspecific, quick (minutes to hours)
Includes epithelium, secreted products, phagocytes, NK cells, plasma proteins (complement, acute phase proteins), some cytokines
Adaptive immunity
Occurs on exposure to specific antigens, days to weeks
Includes lymphocytes, their secreted proteins (antibodies, cytokines), “antigen-presenting cells” (macrophages)
Divided into “humoral” and “cellular” components
Provides “memory” of prior exposures
type of immunity that Occurs on exposure to specific antigens, days to weeks
Adaptive immunity
adaptive immunity is divided into what two components?
“humoral” and “cellular” components
type of immunity that Provides “memory” of prior exposures
Adaptive immunity
What is an antigen?
A substance that is recognized as foreign (“non-self”) and provokes an immune reaction
what are Autoantigens ?
Autoantigens are self-molecules that inappropriately provoke an immune reaction
what are allergens?
antigens that provoke hypersensitivity responses (allergic response)
Small part of an antigen that interacts with a specific antibody or immune cell antigen receptor
Epitope
