EXAM 1 Cell and Molec Flashcards
helps DNA condense into chromatin
histones
mRNA is synthesized here
nucleus
these allow organ formation and cell to cell interaction
intercellular junctions
highest strength of intercellular junctions
tight junctions
intercellular junction that helps adhere to basil lamina
hemidesmosome
intercellular junctions that allow small molecule passage
gap junctions
in cell membrane, center of bilayer is _____.
hydrophobic
proteins that penetrate into cell membrane
integral
hydrophilic proteins associated with outside of membrane
peripheral
microtubules and microfilaments are what type of proteins?
cytoskeletal proteins
functions of cytoskeletal proteins
maintain shape, allow movement, facilitate polarity, cytotoxic transport
examples of muscular motors
actin, myosin, dyenin, kinesin
vesicles that contain large amounts of lytic enzymes
lysosomes
lysosomes role
degrade molecules
site of most ATP production
mitochondria
B-oxidation and oxidative phosphorylation occur here
mitochondria
when nucleotides are degraded what is produced?
URIC acid
what causes gout?
accumulation of uric acid
in chemotherapy why do patients uric acid levels climb?
a lot of cell death occurring
formed from a SINGLE chain of nucleotides
RNA
secreted proteins are made on the ________
endoplasmic reticulum
coding parts of DNA are called____.
EXONS
noncoding parts of DNA are called ____.
INTRONS
Deamination yields _____.
urea
what starts Urea cycle?
NH4
lab tests that are important functions of liver damage
ALT, AST
When the Krebs cycle is unable to process acetyl-coA, what is produced?
KETONES
If there are ketones in urine, pt is using a high level of ____ for energy.
fat
pathway that uses amino acids and turns it back into glucose
gluconeogenesis
Energy source in fat
long carbon chains
In B-oxidation, for each acetyl- coA, we can obtain ___ ATP
18
process where glycogen can be turned back into glucose
glycogenolysis
pathway that starts with pyruvate and will end up with 36 ATP per glucose
Krebs cycle
does glycolysis require oxygen?
no
pathway where we get 2 ATP per glucose molecule
glycolosis
the ultimate source of energy for biological reactions are compounds with _____.
high-energy phosphate bonds
what is normal plasma osmolality?
285-295 mOsm/kg
osmolality is calculated by what three compounds in blood?
sodium, glucose, blood-urea nitrogen
causes cells to swell
hypotonic solution
solution that causes cell to shrink
hypertonic
primary cation in ECF
sodium
primary anion in ECF
chloride
primary cation in ICF
potassium
how do capillaries separate blood from interstitial fluid?
basement membranes
blood and interstitial fluid make up the _____.
extracellular fluid
makes up 2/3 of total body fluid
intracellular fluid
% of blood plasma in human fluid
5%
ECF and ICF make up what percent of body weight?
55-65%
normal somatic cells are _____.
diploid
phase in mitosis where initial cell growth begins
G1
mitosis phase that most cells are in
G0
dna synthesis occurs to form tetraploid cells in this phase of mitosis
S phase
mitosis phase that has continued cell growth before division
G2
cell division phase of mitosis
M Phase
cell proliferation in germ cells is done by ____.
meiosis
in meiosis, chromatids separate to form how many haploid cells?
4