[Exam 4] Chapter 37 – Infectious or Communicable Disorder Flashcards
What do Phagocytic cells do?
First line of defense upon invasion of bacteria
Function of Lymphocytes?
Main source of producing an immune response, responds to viral infections
Function of Monocytes?
SEcond line of defense, and responds to larger and more severe infections
Infectious Process: What does the cellular response involve?
Arrivial of WBCs to the are.
Infectious Process: WBCs use phagocytosis for what?
Ingesting and destroying pathogen.
Infectious Process: What happens if bacteria escapes phagocytosis?
Enters blood stream and immune system activated.
Infectious Process: What to B / T cells do?
B: Produce antibodies
T: Attack the antigen directly.
They both will rememebr teh antigen.
Infectious Process, Fever: Infection by bacteria triggers endogenous pyrogens, what does what?
Trigger prostaglandin production and increases bodies temp set point. Results in shiver, that allows body temp to rise.
Infectious Process, Fever: What is used to decrease fevers?
Antipyretics to lower fever and increase comfort. Temp lower by inhibiting production of prostaglandin. Sweating results.
Infectious Process, Fever: When does hyperthermia occur?
When norml thermoregulation fails, with unregulated rise in core temp. CNS impaired here.
Infectious Process, Fever: Bodi produces a natural antipyretic, called what
Cryogen. Without this, body will rise above 105.8
Infectious Process, Chain of Infection: Poor hygiene habits include
lack of handwashing, placing toys in mouth, drooling, and leaking diapers
Infectious Process, Chain of Infection: What is incubation?
Time from entrance of pathogen into the body to appearance of first symptoms
Infectious Process, Chain of Infection: What is Prodrome?
Time of onset of nonspecific symptoms such as fever, fatigue
Infectious Process, Chain of Infection: What is Convalescence?
Time when acute symptoms of illness disappear
Infectious Process, Chain of Infection: What is a reservoir?
Place where pathogens can thrive and reproduce, such as human body or animals
Infectious Process, Chain of Infection: What is portal of exit?
Way for pathogen to exit the reservoir, such as skin or mucous membranes
Infectious Process, Chain of Infection: what is mode of transmission?
Direct transmission, such as body to body or indirect, such as through droplets
Infectious Process, Chain of Infection: Tier 1 for Hospital Infection Control?
Stand precautions, which is made for all children regardless of conditions
Infectious Process, Chain of Infection: Tier 2 for Hospital Infection Control?
Transmision based precautions, designed for children who are known or suspected to be infected.
Infectious Process, Health Hx: When eliciting history of present illness, inquire about what?
Exposure to infection
Immunization hx
Fever
Sore Throat
Lethargy
Vomiting
Infectious Process, Health Hx: Why would hydration be used?
Child who is vomiting or has diarrhea. They can replace these losses
Infectious Process, Health Hx: Why would fever reduction eb done?
Feibrile child who can’t keep up with increased metabolic demands
Infectious Process, Health Hx: Examples of Antipyretics?
Acetaminophen and Ibuprofen
Infectious Process, Inspection/Observation: Lethargy can indicate what?
Serious infection or sepsis.
Infectious Process, Inspection/Observation: How to assess hydration status?
Inspect oral mucosa, dry and pale mucous membranes, and observe for sunken eyes
Infectious Process, Palpation: Palpation of what shows dehydration
Tugor, and if the fontanels are sunken.
Infectious Process, Labs: Where should blood draws be done?
Area other that child’s bed, such as treatment room. Bed should be kept as an “Safe” area.
Infectious Process, Labs: What does C-Reactive Protein (CRP) test for?
Measures for type of protein produced in livere present during acute inflammation
Infectious Process, Labs: Why is stool culture done?
To determine if bacteria or parasite has infected the intestines
Infectious Process, Labs: Usual sites for obtaining blood ?
Superficial veins of the dorsal surface of the hand or the antecubital fossa. Jugular/Femoral vein may also be used.
Infectious Process, Labs: What to know for fingerprint puncture?
Directed to the sides of the fingertop. Great toe puncture done the same way.
Infectious Process, Managing Fever: Fears of fever can lead to mismanagement of fever, including?
Inappropriate dosing of antipyretics, awakening at night to give pyretics, or inappropriate use of nonpharmacologic treatment
Infectious Process, Managing Fever: Infants younger than 3 months with rectal temperature greater than 38 degrees C should be seen why?
Considered at risk for sepsis until proven otherwise, due to immature immune system
Infectious Process, Managing Fever: Major benefit of decreasing fever is what?
Increasing comfort in child and decreasing fluid requirements.
Infectious Process, Managing Fever: Why should you never give Aspirin to child?
Due to risk of Reye Syndrome
Infectious Process, Managing Fever: Causes of acetaminophen toxicity include?
Overdosing or incorrect dosing due to failure to understand label.
Infectious Process, Managing Fever: Why may there be an issue with alternating Ibuprofen/Acetaminophen?
Parents forget which medication is given every 4 hour, and which one is given every 6 hours.
Infectious Process, Managing Skin Rashes: What can relieve itching?
Cool compresses or cool baths
Sepsis: What is this?
Systemic overresponse to infection resulting from bacteria and viruses.
Sepsis: This leads to septic shock, which causes what?
Hypotension, low blood flow, and multisystem organ failure.
Sepsis: What causes this in younger and older children?
Younger <3 Months: E. Coli. Group B Strep, S. Aureus. Herpes
Older: N Meningitidis, S. Pneumoniae, S. Aureus
Sepsis: Who’s at risk for this
Infants < 3 months, immunocompromised children, and children with indwelling vascular catheter
Sepsis - Patho: How does this occur?
Results from floating toxins, mediated by cytokine release. Causes overproduction of proinflammatory cytokines
Sepsis - Patho: What results from excessive cytokine release?
Impaired pulmonary, hepatic, or renal function
Sepsis - Therapeutic Mx: How are infants treated?
In hospital. Admitted for close monitoring with antibiotic therapy. IV Antibiotics started immediately after blood, urine, and CSF.
Sepsis - Therapeutic Mx: How long is treatment done for?
When negative results occur. Usually after 72 hours. If not responding to treatment, sepsis may be progressing to shock.
Sepsis - Health Hx: Common signs and symptoms?
Child may not lok like
Crying more than usual
FEver
Lethargic
Poor feeding
Rash
Difficulty breathing
Seizures
Sepsis - Health Hx: Risk factors to look at?
Prematurity, lack of immunizations, immunocompromise
Sepsis - Health Hx: In young infants, pregnancy and labor risk factors to look at include?
Premature rupture of membranes
Difficult delivery
Maternal infection
Sepsis - Health Hx: Sepsis may occur in hospitalized child, with risk factors including what?
Intensive care unit stay
Presence of central line
Sepsis - Physical Exam, Inspection/Observation: How will they appear?
Lethargic, pale, and show signs of dehydration