[Exam 1] Chapter 20 - Pregnancy at Risk: Selected Health Conditions and Vulnerable Populations Flashcards
Diabetes Mellitus: What is this?
Characterized by a relative lack of insulin or absence of the hormone that is necessary for glucose metabolism
Diabetes Mellitus: What is Type 1 Diabetes??
Insulin resistance or deficiency (autoimmune process). Usually before age of 30.
Diabetes Mellitus: What is Type 2 Diabetes?
Insulin resistance or deficiency (related to obesity, sedentary lifestyle).
Diabetes Mellitus: What is Impaired Fasting Glucose and Impaired Glucose Tolerance
Characterized by hyperglycemia at a lower level that what qualifies for diabetes (fasting blood glucose between 100 and 125, and blood glucose between 140 and 199 after 2 hour test.)
Diabetes Mellitus: What is Gestational Diabetes Mellitus?
Glucose intolerance with its onset during pregnancy usually around the 24th week or first detected in pregnancy
Diabetes Mellitus: During pregnancy, diabetes is classified into what two groups?
Pregestational diabetes which includes women with type 1 or type 2 diabetes
Gestational diabetes, which develops during pregnancy
Diabetes Mellitus: Gestational diabetes is associated with what complications?
Neonatal complications such as macrosomia, hypoglycemia, and birth trauma
Maternal comps such as preeclampsia and casarean birth
Diabetes Mellitus Patho: Understanding the patho of gestational diabetes involves what two components?
Those are the existence of pancreatic beta-cell dysfunction prior to pregnancy and unmasking of this problem by development of insulin resistance during pregnancy
Diabetes Mellitus Patho: Normal pregnancy is characterized by what to insulin?
Increasing peripheral resistance to insulin and a compensatory increase in insulin secretion
Diabetes Mellitus Patho: What happens in direct correlation with growth of placental tissue?
More placental hormones are secreted such as Human Placental Lactogen (hPL) and Growth Hormone (Somatotropin). Insulin increases to overcome this.
Diabetes Mellitus Screening: What is recommended for women to take screening wise?
Risk analysis of all pregnant women at their first prenatal visit and additional screening of all high-risk pregnant women again at 24-28 weeks.
Diabetes Mellitus Screening: Which pregnant women do not need to be screened at their first prenatal visit?
No history glucose intolerance
Less than 25 years
Normal body weight
No family history
Diabetes Mellitus Screening: What elevations can indicate diabetes?
Elevated glycosylated hemoglobin.
and Combining HbA1c and Plasma glucose
Diabetes Mellitus Screening: Typically, screening is based on what?
75g 1-hour glucose challenge test between weeks 24-28. Level above 140 is abnormal.
Diabetes Mellitus Screening: What are the normal testing values for fasting, 1,2,3 hour.
Fasting = <92
1 Hour = < 180
2 Hour = <153
3 Hour = < 140
Diabetes Mellitus and Care for Woman with Pregestational Diabetes: What is generaly the foundation of exercise for someone with GDM?
Diet -> Sometimes Insulin Exercise -> Fetal Surveillance
Diabetes Mellitus and Care for Woman with Pregestational Diabetes: Goals of precocnception care is what?
Integrate the woman into management of diabetes
Achieve the lowest glycosylated hemoglobin A1C
Ensure effective contraception
Identify and evaluate long-term diabetic complications
Diabetes Mellitus and Care for Woman with Pregestational Diabetes: What is Glycosylated Hemoglobin (HbA1C) and what are the good ranges?
Measurement of the average glucose levels during the past 100 to 120 days. <7% indicates good control. >8% indicates poor control and warrants intervention
Diabetes Mellitus and Care for Woman with Pregestational Diabetes: Most common malformations associated with diabetes occur in what systems?
Renal, cardiac, skeletal, and CNS
Diabetes Mellitus and Care for Woman with Gestational Diabetes: ADA recommends maintaining a fasting glucose in what range?
Below 92 fasting
1 hour below 180
2 hour below 153
Diabetes Mellitus and Care for Woman with Gestational Diabetes: Tight control has been advocated with a reduction of ?
Macrosomia
Diabetes Mellitus and Care for Woman with Gestational Diabetes: Nutritional management focuses on?
Maintaining balanced glucose levels and providing enough energy and nutrients for pregnant woman, while avoiding ketosis and minimizing risk of hypoglycemia
Diabetes Mellitus and Care for Woman with Gestational Diabetes: What content of carbohydrates is recommended?
40%
Pharmacologic Therapy for Woman with Gestational Diabetes: How often is insulin given?
Two doses given daily with 2/3 of total insul in morning to cover energy needs of the active day
Pharmacologic Therapy for Woman with Gestational Diabetes - Oral Meds: What has been promising?
Glyburide and Metformin because they do not cross the placenta
Pharmacologic Therapy for Woman with Gestational Diabetes - Oral Meds: ACOG recommends use of diet or insul or oral diabetic meds to achieve 1-hour postprandial blood glucose level of
130 mg/dL
Pharmacologic Therapy for Woman with Gestational Diabetes - Oral Meds: What does exercise do for body?
Helps maintian glucose control by increasing the uptake of glucose into the cells and decreasing central obesity, hypertension, and dyslipidemia, which will ultimately decrease womans insulin requirements
Pharmacologic Therapy for Woman with Gestational Diabetes - Oral Meds: Maternal benefits of exercise include
improved cardiovascular function, limited pregnancy weight gain, decreased musculoskeletal discomfort, and reduced incidence of muscle cramps
Pharmacologic Therapy for Woman with Gestational Diabetes - Oral Meds: Fetal beenfits of exercise include
decreased fat mass, improved stress tolerance, and advanced neurobehavioral maturation
Pharmacologic Therapy for Woman with Gestational Diabetes - Insulin: Reduced in first trimester why?
To prevent hypoglycemia resulting from increased insulin sensitivity as well as from N/V.
Pharmacologic Therapy for Woman with Gestational Diabetes - Insulin: Which insulins are used?
Lispro (Humalog) and Aspart (NovoLog) because they do not cross the placenta, reduce postprandial hyperglycemia and episodes of hypoglycemia between meals
Pharmacologic Therapy for Woman with Gestational Diabetes - Insulin: Target glucose range for fastign and 1 hour?
60-90 mg/Dl and 1 hour = 120 mg/dL