Exam 4: Bipolar Flashcards

1
Q

Manic Episode

A

dramatic and inappropriate rises and mood out of proportion to the actual happenings in someone’s life; can be happy and euphoric or irritable and angry

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2
Q

Hypomanic Episode

A

less severe symptoms of mania that cause little impairment, changed mood for at least 3 days, uncharaceristic of normal personality, observable by others

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3
Q

Diagnosis

A

3 or more symptoms (4 for irritability) during manic episode: inflated self esteem/grandiosity, decreased need for sleep, more talkatibe, flight of ideas, distractability, increased activity/agitation, excessive involvement in activities; marked impairment in functioning, or necessary hospitaization to self/others

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4
Q

Bipolar I

A

at least 1 manic episode, may be hypomanic, almost always a major depressive episode

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5
Q

Bipolar II

A

at least 1 depressive episode, at least 1 hypomanic episode, no manic episode

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6
Q

Cyclothymic Disorder

A

frequent mild depression and frequent hypomania; symptoms at least half of the time for at least 1 years (adults) or 1 year (children/adolescents)

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7
Q

Age of Onset

A

average adolescence/early adulthood, diagnosis between 15-44
Bipolar I: 18
Bipolar II: 19-22

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8
Q

Prevalence: Lifetime Bipolar

A

up to 4% (less common than depression)

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9
Q

Prevalence: Lifetime Cyclothymic

A

.4-1%

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10
Q

Prevalence: 1 yr. Bipolar I

A

.6%

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11
Q

Prevalence: 1 yr. Bipolar II

A

.8%

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12
Q

Gender Patterns

A

m = f, but first episode is more likely depression in females and mania in males, females more likely to have depressie episodes and cycle more rapidly through episodes

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13
Q

Comorbidity (Bipolar I and II)

A

substance abuse, eating disorders, ADHD, panic disorder, social anxiety, higher suicide rates, bipolar II: BPD

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14
Q

Bipolar in Children

A

often used as catch-all category for aggressive kids (disruptive mood dysregulation disorder has become a more common diagnosis), over-diagnosis caused overmedication with meds not tested in kids

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15
Q

Psychodynamic Theory

A

mania as a defense against depression and low self esteem

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16
Q

Biological Theory: Neurotransmitters

A

norepinephrine/serotonin overactivity or difference in receptors; seems to be associated with less serotonin but neurotransmitter role is unclear and generally unsupported

17
Q

Biological Theory: Sodium Ion Instability and Membrane Permeability

A

Lithium (blood salt) as major treatment effective in moderating mood swings and regulating bipolar and MDD; theory suggests that Na+ does not properly flow in and out of membrane properly during action potential; now a revised hypothesis including calcium; membrane permeability problems including Protein Kinase C

18
Q

Biological Theory: Genetics

A

higher heritability in bipolar than depression but does not completely account; twins: MZ 70% DZ 30% (larger gap between MZ and DZ); 25% first degree relatives have mood disorder (usually depression)