π€°πΎ- Exam 4 Flashcards
Asphyxia
Insufficient oxygen and excess carbon dioxide in the blood and tissues
Factors contributing to asphyxia
Preterm lungs with insufficient surfactant
Maternal (hypertension, infection, drug use)
Placental (placenta previa, abruptio placentae, postmaturity)
Fetal (cord problems, infection, premature birth, multifetal gestation)
Transient tachypnea of the newborn
Risk factors, manifestations
(Retained lung fluid)
Risk factors- cesarean, macrosomia, multiple gestation, excessive maternal sedation, prolonged or precipitous labor, make gender and maternal diabetes or asthma
Manifestations- develops within 6hrs of birth, grunting, retractions, nasal flaring and mild cyanosis
Infertility
Inability to conceive after 1 year of unprotected regular sexual intercourse
Primary vs secondary infertility
Primary- never conceived
Secondary- unable to conceive a second time
What are the 4 factors contributing to infertility in males
Abnormal sperm
Abnormal erections
Abnormal ejaculation
Abnormal seminal fluid
Causes of abnormal sperm
- Hormonal
- Chronic illness (mumps, cirrhosis, renal failure)
- infection of the genital tract
- varicocele or obstruction of the ducts that carry sperm to the penis
- exposure to toxins (lead, pesticides)
- antineoplastic drugs or radiation
- excessive alcohol intake
- use of illicit drugs (marijuana or cocaine)
- elevated scrotal temp (fever, saunas, hot tubs, sitting prolonged periods)
- immunologic factors
Causes of abnormal erections
Influenced by physical and psychological factors
Causes: CNS dysfunction , surgery, disorders affecting the spinal cord, PVD reduces a amount of blood entering the penis, antihypertensives or antidepressants may reduce erection or shorten duration
Retrograde ejaculation
Causes
Release of semen backward into the bladder
Causes: DM, neuro disorders, surgery that effects sympathetic nerves, antihypertensives and psychotropics, hypospadias, anxiety
Abnormal seminal fluid
Semen coagulates immediately after ejaculation but liquefies within 60 mins , permitting forward movement of sperm
Seminal fluid that remains thick traps the sperm , impeding their movement into the cervix
What are the 9 factors contributing to infertility in females
1 disorders of ovulation: altered secretion of the hormones
2 abnormalities of the Fallopian tube: tubal obstruction
3 abnormalities of the cervix: damaged or incompetent, abnormal mucous
4 abnormalities of the uterus: stenosis or congenital malformations
5 abnormalities of fetal chromosomes
6 endocrine abnormalities: inadequate progesterone secretion, diabetes or thyroid disorders
7 immunological factors: lupus, mother rejects embryo
8 environmental agents
9 infections of the reproductive tract
Gnrh, FSH , LH
Gonadotropin-releasing hormone: stimulates the pituitary to release FSH and LH
follicle-stimulating hormone: stimulates maturation of follicles in the ovary, mature follicles causes the ovary to secrete estrogen to thicken the endometrium
Luteinizing hormone: 24-36 hours BEFORE ovulation LH stimulates final maturation and release of one ovum from its follicle
Evaluation of infertility
History & reproductive history
Physical exam
Diagnostic tests: start with simple, least invasive, less expensive (males- semen analysis, females- ovulation monitoring, basal temp, cervical mucus)
Chromosomal analysis if repeated losses occur
What are the therapies used to facilitate pregnancy
Medications
Surgery
Insemination: sperm is placed into uterus
Egg donation: donor egg
Surrogate parenting
Clomiphene citrate
Clomid
Induces ovulation by increasing frequency of GnRH secretion from the hypothalamus, thus increasing FSH and LH release
Bromocriptine
Parlodel
Corrects excess prolactin secretion by anterior pituitary , improving LH and FSH secretion
hCG
Causes the corpus luteum to release progesterone to maintain the pregnancy
Ovarian hyperstimulation syndrome
Caused by too much hormone secretion
Ovarian enlargement with exudation if fluid and protein into the womanβs peritoneal and pleural cavities
In vitro fertilization
Maybe done to bypass blocked or absent Fallopian tubes
Removal of the ova and mix with sperm and return to the uterine cavity AFTER fertilization
Gamete intrafallopian transfer
Sperm and ova are injected into Fallopian tube
Zygote intrafallopian transfer
Aka tubal embryo transfer
Fertilized ova is placed in Fallopian tube
What type of contraceptives should be avoided in perimenopausal women and why
No oral contraceptives due to increased risk of stroke and coronary artery disease
Vasectomy
Male sterilization by cutting a section of the vas deferens, which carries spent from the testes to the penis
ParaGard vs Mirena
ParaGard - (the copper T 380A) is effective for 10years
Mirena - (levonorgestrel intrauterine System) is effective for 5 years
more effective that any other contraceptive
Action of Mirena
Continuously releases progestin , which thickens cervical mucus and prevents transport of sperm into the endometrial cavity and Fallopian tubes
Side effects / contraindications / teaching for Mirena
Side effects- cramping and bleeding following insertion, menorrhagia, dysmenorrhea , irregular bleeding or spotting , amenorrhea
Contraindications- ectopic hx, bleeding disorders, pelvic infections, abnormal uterus
Teaching- side effects, check for presence of string every month
Implanon
A single rod implant, inserted SQ into the upper inner arm
Releases progestin continuously to provide 3 years of contraception
Acts to inhibit ovulation, thicken cervical mucus and makes endometrium unfavorable for implantation
Depo-provera
Injectable PROGESTIN available IM or SQ
prevents ovulation for 15wks, injections should be scheduled every 13wks
Side effects- menstrual irregularities, amenorrhea , weight gain, headaches, depression, hair loss nervousness, decreased libido, breast discomfort and decreased bone density
increases quantity of milk in lactating women
Combination OCs
Contain estrogen and progestin
Most common
Cause thickening of cervical mucus , suppress production of LH and FSH
Results in shorter, lighter periods
Progestin only pills
Minipill
Taken daily with no hormone-free days
Less effective in inhibiting ovulation but causes thickening of cervical mucus and makes endometrial lining unfavorable for implantation
Emergency contraceptive
Morning after pill
(Plan b one-step, next choice, next choice one dose)
Work by delaying or inhibiting ovulation, thickening cervical mucus and interfering with the function of the corpus luteum
take within 120hrs (5 days) of unprotected sex
Oral contraceptives warning signs ACHES
A - abdominal pain (mesenteric or pelvic vein thrombosis)
C- chest pain, dyspnea, hemoptysis, cough (PE or MI)
H- severe headaches, weakness, numbness of extremities, HTN (stroke, migraine)
E- eye problems/loss of vision (retinal vein thrombosis, stroke, migraine)
S- severe leg pain or swelling in calf or thigh, heat, redness (DVT)
Contraceptive vaginal ring
Common side effect
NuvaRing
Soft, flexible vinyl ring containing estrogen and progestin inserted for 3 weeks and 1 week is ring-free
COMMON SIDE EFFECT: headache π€
Prescription is needed
Transdermal contraceptive patch
Ortho evra
Estrogen & progestin skin patch that suppresses ovulation and thickens cervical mucus
New patch applied to a different site weekly for 3 weeks and removed for 1 week
Barrier methods
Chemical vs mechanical
Prevent sperm from entering the cervix by destroying or creating a partition ; avoids use of systemic hormones
Chemical- spermicides (cream or gel) , foams, tablets, films or suppositories
Mechanical- male & female condoms, sponge, diaphragm and cervical cap
Cervical cap
Fem cap
Placed over the cervix to prevent sperm from entering. With spermicide on each side
Smaller than diaphragm
size fitted by health care provider
Can remain in place for 48hrs , donβt remove before 8hrs after sex
Diaphragm
Latex dome surrounded by a spring or coil
Fitted by healthcare provider
Pressure on the urethra May cause irritation and UTI
Bigger than cervical cap
Kept in place 6hrs before and after sex
Mittelschmerz
Pain on ovulation