Exam 4 Flashcards

1
Q

The amount of a chemical that causes injury is often dependent upon dosage. Which of the following best describes dosage in this context?

a. The distribution of the chemical in the environment 
b. The list of toxic chemicals produced by the EPA
c. The amount of chemical /kg of body weight
d. The amount of cell injury the chemical causes
A

c. The amount of chemical /kg of body weight

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2
Q

Children are at higher risk of negative effects from lead exposure because…

a. They eat more fish 
b. They absorb more from food
c. They get vaccinated more often 
d. They are exposed to batteries more often
A

b. They absorb more from food

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3
Q

The symptoms of mercury poisoning are:

a. Anemia, mental deterioration, abdominal pain 
b. Decreased ATP production, increased ROA, cardiac problems
c. Obstructive lung disease, renal toxicity, osteoporosis
d. Tremor, gingivitis, bizarre behavior
A

d. Tremor, gingivitis, bizarre behavior

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4
Q

Toxin exposure can result in which of the following?

a. Excretion of the toxin soon after exposure
b. Storage of the toxin within the body 
c. Transformation into a reactive form of the toxin within the body 
d. All of the above
A

d. All of the above

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5
Q

Arsenic poisoning cases disruption in:

a. Oxidative phosphorylation 
b. RBC production 
c. Gas transfer in lungs
d. Bone healing
A

a. Oxidative phosphorylation

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6
Q

Coal miners are exposed to large amounts of coal dust in the air. Without proper respirators, they are at risk of developing which of the following conditions?

a. Chloracne
b. Hepatitis
c. Pneumoconiosis
d. Marasmu
A

c. Pneumoconiosis

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7
Q

Which of the following cancers is associated with cigarette smoking?

a. Bone 
b. Brain 
c. Skin 
d. Esophagus
A

d. Esophagus

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8
Q

Smoking contributes to emphysema because the constant irritations produces inflammation and recruits neutrophils. The neutrophils release _______ which damages the lungs.

a. Phenol 
b. Elastase
c. Carbon monoxide
d. Lipids
A

b. Elastase

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9
Q

Ethanol causes fat accumulation in the liver that can lead to cirrhosis. This happens beau alcohol dehydrogenase causes….

a. Production of ROS and lipid oxidation in the liver
b. Changes n the NADH/NAD+ ratio
c. Acetaldehyde production 
d. Release of endotoxin from gram negative bacteria
A

b. Changes n the NADH/NAD+ ratio

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10
Q

Which of the following is an adverse drug reaction?

a. Alcohol toxicity from binge drinking
b. An allergic reaction to penicillin 
c. Fetal hypoxia from cocaine use by the mother
d. All of the above
A

b. An allergic reaction to penicillin

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11
Q

Cocaine inhibits the re-uptake of what neurotransmitter in central nervous system synapses?

a. Epinephrine
b. Serotonin 
c. Dopamine
d. GABA
A

a. Epinephrine

c. Dopamine

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12
Q

Before James Lind realized that citrus fruit could help, sailors had enough food for long voyages, but they often suffered from scurvy due to a lack of vitamin C. This problem is a type of ….

a. Primary malnutrition 
b. Secondary malnutrition 
c. Neither
d. Both
A

a. Primary malnutrition

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13
Q

Kwashiorkor is a type of protein energy malnutrition. People with this condition have rounded abdomens because of…..

a. Muscle loss
b. Hypoalbuminemia
c. Renal insufficiency 
d. Cachexia
A

b. Hypoalbuminemia

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14
Q

Bell is having problems with dry eyes, infections, and driving at night. Bell’s conditions could be caused by which of the following deficiencies in her diet?

a. Vitamin A
b. Vitamin C
c. Vitamin D
d. Protein
A

a. Vitamin A

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15
Q

What happens following a decrease in vitamin D absorption or production?

a. Increased calcium and phosphate levels in the blood 
b. Increased calcium absorption in the intestine
c. Increased parathyroid hormone
d. Decreased parathyroid hormone
A

c. Increased parathyroid hormone

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16
Q

Increased body weight due to adipose tissue accumulation that is of sufficient magnitude to cause adverse health effects is the definition of…..

a. Obesity 
b. BMI
c. Body fat %
d. Overweigh
A

a. Obesity

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17
Q

Bill and his doctor are discussing his recent weight gain. Which of the following factors might his doctor mention as a possible influence on Bill’s weight?

a. His family history 
b. The state of his microbiome 
c. Osteoarthritis
d. Massive obesity
A

d. Massive obesity

18
Q

Leptin sends a signal to the brain that causes….

a. Decrease in food intake 
b. Decrease in energy expenditure
c. Osteoarthritis
d. Massive obesity
A

a. Decrease in food intake

19
Q

Influenza virus is transmitted through aerosols and through person to person contact. What is the most likely route of infection for this respiratory virus?

a. Ingestion 
b. Inhalation 
c. Sexual transmission 
d. Injection
A

b. Inhalation

20
Q

What is keratitis?

a. Inflammation of the cornea
b. Inflammation of the skin 
c. Inflammation of the iris 
d. Inflammation of the finger and toe nails
A

a. Inflammation of the cornea

21
Q

A hysterectomy is….

a. Removal of hypothalamus 
b. Removal of the hyoid bone 
c. Removal of the uterus
d. Removal of gonads
A

c. Removal of the uterus

22
Q

Oliguria is…..

a. Production of large amounts of protein 
b. Production of small amounts of urine 
c. Production of large amounts of nitrogen 
d. Production of small amounts of blood
A

b. Production of small amounts of urine

23
Q

A melanocyte is a …..

a. Cell which produces a dark pigment
b. Cell which softens the tissue by being fill of fat
c. Cell which produces mucus
d. Transformed cell from a skin tumor
A

a. Cell which produces a dark pigment

24
Q

Pili and Protein F contribute to bacteria virulence in what was?

a. They aid in adherence
b. The help bacteria invade host cells
c. They are toxins
d. They make biofilms
A

a. They aid in adherence

25
Q

Biofilms are important in human health because bacteria in biofilm are….

a. Working together with viruses
b. More antibiotic resistant 
c. Using quorum sensing to communicate
d. Reproducing faster
A

b. More antibiotic resistant

26
Q

In which of the following infections is the damage to the host caused by the host’s own immune response?

a. Toxin-producing Clostridium difficile 
b. Hepatitis B
c. HIV
d. Protease-producing Staphylococcus aureus
A

b. Hepatitis B

27
Q

The most successful way human micro biome research has impacted clinical practice to date is…..

a. Using probiotics to treat obesity 
b. Curing recalcitrant C. diff infections with fecal microbiota transplants
c. Altering brain chemistry of anxious mice
d. Using probiotics to improve micro biome healt
A

b. Curing recalcitrant C. diff infections with fecal microbiota transplants

28
Q

Which of the choices is used to group viruses?

a. Herpes viruses and HIV viruses
b. Capsid-makers and non-capsid makers
c. DNA and RNA
d. Retroviruses and polio viruses
A

c. DNA and RNA

29
Q

The tropism of HIV is….

a. CD4+ cells
b. CD8+ cells
c. CD3+ cells
d. CXC+ cells
A

a. CD4+ cells

30
Q

Interferons act against viral replication by….

a. Blocking production of proteins
b. Blocking entrance into the cell 
c. Blocking entrance into the nucleus
d. Blocking lysis of the cell
A

a. Blocking production of proteins

31
Q

Quorum sensing is a word used to describe….

a. Bacterial infection 
b. Bacterial virulence
c. Bacterial communication 
d. Bacterial colonization
A

c. Bacterial communication

32
Q

An example of bacterial endotoxin is…..

a. Lipopolysaccharide
b. Toxin A
c. Protein F
d. Interferon alpha
A

a. Lipopolysaccharide

33
Q

Pathogens can be prevented from infecting hosts by…..

a. Antimicrobial peptide production 
b. Interferon production 
c. Being outcompeted by normal microbiota
c. All of the above
A

c. Being outcompeted by normal microbiota

34
Q

Which of the bacterial behaviors below is used to avoid the immune system?

a. Produce interferons
b. Making slime coats of capsules
c. Producing toxins
A

b. Making slime coats of capsules

35
Q

Viruses can invade cells by…

a. Type III secretion systems
b. Fusing with the cellular membranes
c. Manipulating the cytoskeleton 
d. Releasing proteases
A

b. Fusing with the cellular membranes

36
Q

A cold sore that heals and reappears during finals week stress is an example of what kind of viral infection?

a. Slow or progressive
b. Latent
c. Chronic
d. Oncogenic
A

b. Latent

37
Q

Some bacteria invade cells by injecting proteins through a needle-like protein appendage. The protein appendage is called a….

a. Protease release system 
b. Phagocyte receptor 
c. Type III secretion system 	
d. Cytoskeleton manipulation
A

c. Type III secretion system

38
Q

Super antigens cause toxic shock syndrome by….

a. Binding to a conserved site on the TCR
b. Causing nerve damage
c. Flooding the bloodstream with LPS
d. Altering signal recognition pathways
A

a. Binding to a conserved site on the TCR

39
Q

Viruses reproducing within infected cells try to hide form the immune system by down regulating MHC class I molecules on infected cells. What part of the immune system can still “catch” these infected cells and kill them?

a. NK cells
b. CTLs
c. T helper cells
A

a. NK cells

40
Q

n the previous section we discussed several viruses that cause cancer. What term below describes a virus that causes the development of cancerous growth?

a. Oncogenic
b. Latent
c. Progressive
d. Chronic
A

a. Oncogenic

41
Q

What is the approximate weight of the normal microbiota of an adult human?

a. 2-6 pounds
b. 2-6 ounces
c. 2-6 miligrams
d. 2-6 kilograms
A

a. 2-6 pounds